merck millipore,默克密理愽
  • merck millipore,默克密理博,382194,HMTase Inhibitor VI, BRD4770 - Calbiochem

  • merck millipore,默克密理博,382194,HMTase Inhibitor VI, BRD4770 - Calbiochem

    产品名称：HMTase Inhibitor VI, BRD4770 - Calbiochem
    产品型号：382194
    The HMTase Inhibitor VI, BRD4770 controls the biological activity of HMTase. This small molecule/inhibitor is primarily used for Cell Structure applications.

    merck millipore,默克密理博,382194,HMTase Inhibitor VI, BRD4770 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,382194,HMTase Inhibitor VI, BRD4770 - Calbiochem

    重要规格表

    经验配方
    C₂₅H₂₃N₃O₃
    描述
    概述 A cell-permeable analog of the amino-benzimidazolo BIX-01338 (Cat. No. 539212) and the methylester prodrug of BRD9539 that acts as an SAM-competitive inhibitor against PRC2 and G9a (IC50 ≤6.3 µM) histone methyltransferase activities, displaying little effect toward 10 other HMTases, 9 HDACs, and 100 cellular kinases. Selectively reduces H3K9me2 and H3K9me3 (EC50 = 5 µM) histone methylation levels in pancreatic cancer cells (PANC-1) with much less or little effect toward H3K36me3, H3K4me3, H3K27me3, or H3K6me3 levels. Inhibits both anchorage-dependent and -independent PANC-1 proliferation via ATM activation and G2/M cell-cycle arrest, but not apoptosis induction (no caspase3/7 activation; 10 µM, 72 h).
    产品目录编号 382194
    品牌系列 Calbiochem®
    同义词 Methyl-2-benzamido-1-(3-phenylpropyl)-1H-benzo[d]imidazole-5-carboxylate, EHMT2/G9a Inhibitor VI
    参考
    参考 Yuan, Y., et al. 2012. ACS Chem Biol. 7, 1152.
    产品信息
    形式 White powder
    Hill配方 C₂₅H₂₃N₃O₃
    Molar Mass 413.5
    可逆 Y
    结构配方图像
    生物信息
    主靶 G9a and PRC2 HMTases
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,382194,HMTase Inhibitor VI, BRD4770 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,111452,邻苯二甲醛
下一件merck millipore产品：merck millipore,默克密理博,MABE584,Anti-phospho-SMC1 (Ser360), clone EPR4498(2), Rabbit Monoclonal Antibody


相关产品

merck millipore,默克密理博,SVGPB1010,Sterivex-GP，0.22 µm，改良聚醚砜，带钟形罩，射线灭菌 merck millipore,默克密理博,SVGPB1010,Sterivex-GP，0.22 µm，改良聚醚砜，带钟形罩，射线灭菌

merck millipore,默克密理博,MABE317,Anti-5-Hydroxymethylcytosine (5hmC) Antibody, clone HMC-MA01 merck millipore,默克密理博,MABE317,Anti-5-Hydroxymethylcytosine (5hmC) Antibody, clone HMC-MA01

merck millipore,默克密理博,GF165,ANG-2 Protein, Human Recombinant merck millipore,默克密理博,GF165,ANG-2 Protein, Human Recombinant

merck millipore,默克密理博,71514,Floating Rack, Maxi merck millipore,默克密理博,71514,Floating Rack, Maxi

merck millipore,默克密理博,111452,邻苯二甲醛 merck millipore,默克密理博,111452,邻苯二甲醛

merck millipore,默克密理博,MABE584,Anti-phospho-SMC1 (Ser360), clone EPR4498(2), Rabbit Monoclonal Antibody merck millipore,默克密理博,MABE584,Anti-phospho-SMC1 (Ser360), clone EPR4498(2), Rabbit Monoclonal Antibody

merck millipore,默克密理博,17-10224,LentiBrite™ GFP-p62 Lentiviral Biosensor merck millipore,默克密理博,17-10224,LentiBrite™ GFP-p62 Lentiviral Biosensor

merck millipore,默克密理博,70003,pBAC™-1 DNA - Novagen merck millipore,默克密理博,70003,pBAC™-1 DNA - Novagen

merck millipore,默克密理博,539560,PKC Inhibitor Peptide 19-36 merck millipore,默克密理博,539560,PKC Inhibitor Peptide 19-36

merck millipore,默克密理博,69278,PCR Markers, 50–2000 bp - Novagen merck millipore,默克密理博,69278,PCR Markers, 50–2000 bp - Novagen


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部