merck millipore,默克密理愽
  • merck millipore,默克密理博,382148,Histone Deacetylase Inhibitor II - CAS 174664-65-4 - Calbiochem

  • merck millipore,默克密理博,382148,Histone Deacetylase Inhibitor II - CAS 174664-65-4 - Calbiochem

    产品名称：Histone Deacetylase Inhibitor II - CAS 174664-65-4 - Calbiochem
    产品型号：382148
    The Histone Deacetylase Inhibitor II, also referenced under CAS 174664-65-4, controls the biological activity of Histone Deacetylase. This small molecule/inhibitor is primarily used for Cell Structure More>>

    merck millipore,默克密理博,382148,Histone Deacetylase Inhibitor II - CAS 174664-65-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,382148,Histone Deacetylase Inhibitor II - CAS 174664-65-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₀H₁₀N₂O₄174664-65-4
    描述
    概述 A cell-permeable second generation hybrid polar agent that acts as a histone deacetylase (HDAC) inhibitor. The HDAC inhibition is believed to arise as a result of the binding of the hydroxamic moiety to the active site zinc. Shown to be a potent inducer of transformed cell growth arrest and terminal differentiation (~4 µM). Induces apoptosis and the CD95/CD95-Ligand expression in human neuroblastoma.
    产品目录编号 382148
    品牌系列 Calbiochem®
    同义词 CBHA, m-Carboxycinnamic Acid bis-Hydroxamide
    参考
    参考 Coffey, D.C., et al. 2001. Cancer Res. 61, 3591.
    Coffey, D.C., et al. 2000. Pediatr. Oncol. 35, 577.
    Marks, P.A., et al. 2000. J. Natl. Cancer Inst. 92, 1210.
    Glick, R.D., et al. 1999. Cancer Res. 59, 4392.
    Richon, V.M., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 3003.
    Richon, V.M., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 5705.
    产品信息
    CAS号 174664-65-4
    具有ATP竞争性 N
    声明 Not available for sale in the United States.
    形式 Off-white solid
    Hill配方 C₁₀H₁₀N₂O₄
    化学配方 C₁₀H₁₀N₂O₄
    Molar Mass 222.2
    可逆 N
    结构配方图像
    生物信息
    主靶 HDAC
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,382148,Histone Deacetylase Inhibitor II - CAS 174664-65-4 - Calbiochem

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