merck millipore,默克密理愽
  • merck millipore,默克密理博,365251,Gö 6983 - CAS 133053-19-7 - Calbiochem

  • merck millipore,默克密理博,365251,Gö 6983 - CAS 133053-19-7 - Calbiochem

    产品名称：Gö 6983 - CAS 133053-19-7 - Calbiochem
    产品型号：365251
    A potent, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase C (PKC) that inhibits several PKC isozymes.

    merck millipore,默克密理博,365251,Gö 6983 - CAS 133053-19-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,365251,Gö 6983 - CAS 133053-19-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₆H₂₆N₄O₃133053-19-7
    描述
    概述 A potent, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase C (PKC) that inhibits several PKC isozymes (IC50 = 7 nM for PKCα and PKCβ; 6 nM for PKCγ; 10 nM for PKCδ; and 60 nM for PKCζ). Gö 6983 does not effectively inhibit PKCµ (IC50 = 20 µM) and can thus be used to differentiate PKCµ from other PKC isozymes.
    产品目录编号 365251
    品牌系列 Calbiochem®
    同义词 2-[1-(3-Dimethylaminopropyl)-5-methoxyindol-3-yl]-3-(1H-indol-3-yl) maleimide, Go 6983
    参考
    参考 Wang, D., et al. 1998. J. Biol. Chem. 273, 33027.
    Stempka, L., et al. 1997. J. Biol. Chem. 272, 6805.
    Gschwendt, M., et al. 1996. FEBS Lett. 392, 77.
    产品信息
    CAS号 133053-19-7
    具有ATP竞争性 Y
    形式 Orange red solid
    Hill配方 C₂₆H₂₆N₄O₃
    化学配方 C₂₆H₂₆N₄O₃
    Molar Mass 442.5
    可逆 Y
    结构配方图像
    生物信息
    主靶 PKCα and PKCβ
    主靶IC50 7 nM for PKCα and PKCβ; 6 nM for PKCγ; 10 nM for PKCδ; and 60 nM for PKCζ
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,365251,Gö 6983 - CAS 133053-19-7 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,ABS159,Anti-HPK1 Antibody


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