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merck millipore,默克密理博,361556,GSK-3 Inhibitor IX, Control, MeBIO - CAS 710323-61-8 - Calbiochem
产品名称：GSK-3 Inhibitor IX, Control, MeBIO - CAS 710323-61-8 - Calbiochem
产品型号：361556
The GSK-3 Inhibitor IX, Control, MeBIO, also referenced under CAS 710323-61-8, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosph More>>
merck millipore,默克密理博,361556,GSK-3 Inhibitor IX, Control, MeBIO - CAS 710323-61-8 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₇H₁₂BrN₃O₂ 710323-61-8 描述 概述 A cell-permeable N-methylated analog of GSK-3 Inhibitor IX, BIO (Cat. No. 361550) that serves as a relevant kinase inactive control (IC50 > 92 µM for Cdk1/B, > 100 µM for Cdk5/p25, and GSK-3α/β). Acts as a potent ligand for aryl hydrocarbon receptor (AhR; EC50 = 20 nM and 93 nM for yeast and hepatoma reporter systems, respectively) and displays antiproliferative properties. 产品目录编号 361556 品牌系列 Calbiochem®
同义词 1-Methyl-BIO 参考 参考 Knockaert, M., et al. 2004. Oncogene 23, 4400.
Polychronopoulos, P., et al. 2004. J. Med. Chem. 47, 935.
Meijer, L., et al. 2003. Chem. Biol. 10, 1255.产品信息 CAS号 710323-61-8 具有ATP竞争性 N 形式 Dark red solid Hill配方 C₁₇H₁₂BrN₃O₂ 化学配方 C₁₇H₁₂BrN₃O₂ Molar Mass 370.2 可逆 N 结构配方图像 生物信息 主靶 Relevant kinase inactive control 主靶IC50 > 92 µM for Cdk1/B, > 100 µM for Cdk5/p25, and GSK-3α/β 纯度 ≥97% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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