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merck millipore,默克密理博,ABE328,Anti-dimethyl Histone H3 (Arg2) Antibody
产品名称:Anti-dimethyl Histone H3 (Arg2) Antibody
产品型号:ABE328
Detect Histone H3 using this rabbit polyclonal antibody, Anti-dimethyl Histone H3 (Arg2) Antibody validated for use in western blotting & Dot Blot.
merck millipore,默克密理博,ABE328,Anti-dimethyl Histone H3 (Arg2) Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE328 描述 Anti-dimethyl Histone H3 (Arg2) Antibody Alternate Names - Histone H3/l
- Histone H3.1
- Histone H3/a
- Histone H3/b
- histone H3/c
- Histone H3/d
- Histone H3/f
- Histone H3/h
- Histone H3/i
- Histone H3/j
- Histone H3/k
背景信息 Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. Histones are modified post-translationally by the actions of enzymes in both the nucleus and cytoplasm. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). The modifications occur predominantly on the N-terminal and C-terminal tails that extend beyond the nucleosome core particle. Histone H3 Arg2 methylation is a widespread silencing modification that inhibits histone H3 Lys4 trimethylation. 产品信息 格式 Affinity Purified 控制 - HeLa acid extract
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect Histone H3 using this rabbit polyclonal antibody, Anti-dimethyl Histone H3 (Arg2) Antibody validated for use in western blotting & Dot Blot. 主要应用 - Western Blotting
应用说明 Western Blotting Analysis: A 1:620 dilution of this antibody detected dimethyl Histone H3 (Arg2) in CARM1 treated dimethyl Histone H3 (Arg2) recombinant protein, but demonstrated a loss of signal in untreated dimethyl Histone H3 (Arg2) recombinant protein. (Note: CARM1 is a methyl transferase that results in the methylation of Histone H3.).
Dot Blot (Specificity) Analysis: A 1:620 dilution from a representative lot detected dimethyl Histone H3 (Arg2) peptides, but not unmethylated Histone H3 (Arg2) or other peptides corresponding to modified histones.
Absurance™ is a trademark of EMD Millipore, Inc.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the N-terminus of human Histone H3 dimethylated at Arg2. 表位 N-terminus 宿主 Rabbit 特异性 This antibody recognizes the N-terminus of Histone H3 dimethylated at Arg2. 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. Broad species reactivity is expected. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_066403
基因符号 - H3FJ
- HIST1H3A
- H3FA
- HIST1H3B
- H3FL
- HIST1H3C
- H3FC
- HIST1H3D
- H3FB
- HIST1H3E
- H3FD
- HIST1H3F
- H3FI
- HIST1H3G
- H3FH
- HIST1H3H
- H3FK
- HIST1H3I
- H3FF
- HIST1H3J
纯化方法 Affinity purified UniProt编号 - P68431
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa acid extract.
Western Blotting Analysis: A 1:620 dilution from a representative lot detected dimethyl Histone H3 (Arg2) in 10 µg of HeLa acid extract.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 200 µL
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