merck millipore,默克密理愽
  • merck millipore,默克密理博,361551,GSK-3 Inhibitor X - CAS 740841-15-0 - Calbiochem

  • merck millipore,默克密理博,361551,GSK-3 Inhibitor X - CAS 740841-15-0 - Calbiochem

    产品名称：GSK-3 Inhibitor X - CAS 740841-15-0 - Calbiochem
    产品型号：361551
    The GSK-3 Inhibitor X, also referenced under CAS 740841-15-0, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applica More>>

    merck millipore,默克密理博,361551,GSK-3 Inhibitor X - CAS 740841-15-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,361551,GSK-3 Inhibitor X - CAS 740841-15-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₈H₁₂BrN₃O₃740841-15-0
    描述
    概述 An acetoxime analog of BIO, GSK-3 Inhibitor IX (Cat. No. 361550) that exhibits greater selectivity for GSK-3α/β (IC50 = 10 nM) over Cdk5/p25, Cdk2/A and Cdk1/B (IC50 = 2.4 µM, 4.3 µM and 63 µM, respectively). Weakly affects the activities of Cdk4/D1 and many other kinases (IC50 ≥ 10 µM). Also acts as an aryl hydrocarbon receptor agonist in both yeast (EC50 ≥ 0.1 µM) and mammalian (EC50 = 0.16 µM) reporter systems.
    产品目录编号 361551
    品牌系列 Calbiochem®
    同义词 (2ʹZ,3ʹE)-6-Bromoindirubin-3ʹ-acetoxime, BIO-Acetoxime
    参考
    参考 Knockaert, M., et al. 2004. Oncogene 23, 4400.
    Polychronopoulos, P., et al. 2004. J. Med. Chem. 47, 935.
    Meijer, L., et al. 2003. Chem. Biol. 10, 1255.
    产品信息
    CAS号 740841-15-0
    具有ATP竞争性 N
    形式 Dark purple solid
    Hill配方 C₁₈H₁₂BrN₃O₃
    化学配方 C₁₈H₁₂BrN₃O₃
    Molar Mass 398.2
    可逆 N
    结构配方图像
    生物信息
    主靶 GSK-3α/β
    主靶IC50 10 nM against GSK-3α/β
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Carcinogenic / Teratogenic
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,361551,GSK-3 Inhibitor X - CAS 740841-15-0 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,CBA024,InnoZyme™ Myeloperoxidase Activity Kit


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