merck millipore,默克密理愽
  • merck millipore,默克密理博,352010,Glutaminase Inhibitor, Compound 968 - Calbiochem

  • merck millipore,默克密理博,352010,Glutaminase Inhibitor, Compound 968 - Calbiochem

    产品名称：Glutaminase Inhibitor, Compound 968 - Calbiochem
    产品型号：352010
    The Glutaminase Inhibitor, Compound 968 controls the biological activity of Glutaminase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

    merck millipore,默克密理博,352010,Glutaminase Inhibitor, Compound 968 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,352010,Glutaminase Inhibitor, Compound 968 - Calbiochem

    重要规格表

    经验配方
    C₂₇H₂₇BrN₂O
    描述
    概述 A cell-permeable benzophenanthridinone compound that acts as an allosteric and reversible inhibitor of mitochondrial glutaminase activity and represses the growth and invasive activity in glutaminase upregulated fibroblasts and in tumor cells (IC50 ≤ 10 µM in NIH3T3 cells stably expressing Dbl, Cdc42-F28L, Rac-F28L or RhoC-F30L mutants and in SKBR3 and MDA-MB231 cancer cells). Shown to effectively shrink tumor size in P-493 B xenografted mouse model (200 µg per inj. i.p., 12 days). Also available as a 10 mM solution in DMSO (Cat. No. 506073).
    产品目录编号 352010
    品牌系列 Calbiochem®
    同义词 5-(3-Bromo-4-(dimethylamino)phenyl)-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a]phenanthridin-4(1H)-one, GAC Inhibitor, GLS1 Inhibitor I, KGA Inhibitor I, Kidney-Type Glutaminase Inhibitor I
    参考
    参考 Wang, J.B., et al. 2010. Cancer Cell 18, 207.
    产品信息
    形式 White powder
    Hill配方 C₂₇H₂₇BrN₂O
    化学配方 C₂₇H₂₇BrN₂O
    Molar Mass 475.4
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,352010,Glutaminase Inhibitor, Compound 968 - Calbiochem

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