merck millipore,默克密理愽
  • merck millipore,默克密理博,344301,sFRP Inhibitor II - CAS 302804-57-5 - Calbiochem

  • merck millipore,默克密理博,344301,sFRP Inhibitor II - CAS 302804-57-5 - Calbiochem

    产品名称：sFRP Inhibitor II - CAS 302804-57-5 - Calbiochem
    产品型号：344301
    The sFRP Inhibitor II, also referenced under CAS 302804-57-5, controls the biological activity of sFRP. This small molecule/inhibitor is primarily used for Activators/Inducers applications.

    merck millipore,默克密理博,344301,sFRP Inhibitor II - CAS 302804-57-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,344301,sFRP Inhibitor II - CAS 302804-57-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₄H₁₇N₃O₄S₂302804-57-5
    描述
    概述 A cell-permeable iminooxothiazolidine compound that is shown to counteract the antagonizing effect of SARP-2/sFRP-1 (secreted frizzled related protein-1) against Wnt-3/frizzled interaction and restore cellular response to Wnt-3 stimulation (by a 2.3-fold enhancement at 15 µM) in U2OS-based reporter assays. Also reported to increase total bone area and the number of osteoblasts (by ~20% and ~45%, respectively) in a murine ex vivo calvarial bone formation assay.
    产品目录编号 344301
    品牌系列 Calbiochem®
    同义词 Wnt Pathway Activator V, 2-(2-(2-Imino-4-oxo-thiazolidin-5-yl)-acetylamino)-4,5-dimethyl-thiophene-3-carboxylic acid ethyl ester, Secreted Frizzled Related Protein-1 Inhibitor II
    参考
    参考 Shi, M., et al. 2009. Bioorg. Med. Chem. Lett. 19, 6337.
    产品信息
    CAS号 302804-57-5
    形式 Off-white solid
    Hill配方 C₁₄H₁₇N₃O₄S₂
    化学配方 C₁₄H₁₇N₃O₄S₂
    Molar Mass 355.4
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,344301,sFRP Inhibitor II - CAS 302804-57-5 - Calbiochem

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