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merck millipore,默克密理博,344216,Formyl Peptide Receptor-Like 1 Agonist, WKYMVm - Calbiochem
产品名称：Formyl Peptide Receptor-Like 1 Agonist, WKYMVm - Calbiochem
产品型号：344216
The Formyl Peptide Receptor-Like 1 Agonist, WKYMVm controls the biological activity of Formyl Peptide Receptor-Like 1. This small molecule/inhibitor is primarily used for Activators/Inducers applicati More>>
merck millipore,默克密理博,344216,Formyl Peptide Receptor-Like 1 Agonist, WKYMVm - Calbiochem
- 产品介绍
描述 概述 A potent chemoattractant that enhances leukocyte activity via activation of Formyl Peptide Receptor-Like 1 (FPRL1). Shown to activate phospholipase C-mediated inositol phosphate formation in human U266 myeloma cells (EC50 = 510 pM). Also shown to stimulate inositol phosphate formation in U937 and HL60 cells, but has no effect on a variety of other cell lines (e.g. NIH3T3, PC12, Daudi, Sp2, Jurkat, H9, Molt-4, SupT-1, K562, and RBL-2H3). Stimulates phagocyte chemotaxis and [Ca2+] flux, and is more effective than fMLP (Cat. No. 05-22-2500) in generating superoxide in human neutrophils. Radioiodinatable at the tyrosine residue. 产品目录编号 344216 品牌系列 Calbiochem®
同义词 H₂N-WKYMV-D-M-CONH₂, FPRL1 Agonist, WKYMVm 参考 参考 Bae, Y.S., et al. 2004. J. Immunol. 173, 607.
Bae, Y.S., et al. 2003. Mol. Pharmacol. 64, 841.
Le, Y., et al. 1999. J. Immunol. 163, 6777.
Seo, J.K., et al. 1997. J. Immunol. 158, 1895.
Baek, S.H., et al. 1996. J. Biol. Chem. 271, 8170.产品信息 具有ATP竞争性 N 形式 Lyophilized 配方 Supplied as a trifluoroacetate salt. Hill配方 C₄₁H₆₁N₉O₇S₂ 化学配方 C₄₁H₆₁N₉O₇S₂ Molar Mass 855.4 吸湿 Hygroscopic
肽序列 H-Trp-Lys-Tyr-Met-Val-D-Met-CONH₂ 可逆 N 生物信息 主靶 Formyl Peptide Receptor-Like 1 主靶IC50 EC50 = 510 pM in activating phospholipase C-mediated inositol phosphate formation in human U266 myeloma cells 纯度 ≥95% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO 肽序列 H-Trp-Lys-Tyr-Met-Val-D-Met-CONH₂ 储存和货运信息 货运代码 Shipped with Blue Ice or with Dry Ice
毒性 Standard Handling
储存 -20°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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