merck millipore,默克密理愽
  • merck millipore,默克密理博,344150,FPT Inhibitor I - Calbiochem

  • merck millipore,默克密理博,344150,FPT Inhibitor I - Calbiochem

    产品名称：FPT Inhibitor I - Calbiochem
    产品型号：344150
    The FPT Inhibitor I controls the biological activity of FPT. This small molecule/inhibitor is primarily used for Cancer applications.

    merck millipore,默克密理博,344150,FPT Inhibitor I - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,344150,FPT Inhibitor I - Calbiochem

    重要规格表

    经验配方
    C₁₉H₂₉NO₆P · 3Na
    描述
    概述 Potent and highly selective inhibitor of farnesyltransferase (FTase; IC50 = 83 nM). Inhibits geranylgeranyltransferase (GGTase) I and II at much higher concentrations (IC50 = 26 µM and 47 µM for GGTase I and II, respectively).
    产品目录编号 344150
    品牌系列 Calbiochem®
    同义词 (E,E)-2-[(Dihydroxyphosphinyl)methyl]-3-oxo-3-[(3,7,11-trimethyl-2,6,10-dodecatrienyl)-amino]propanoic Acid, 3Na
    参考
    参考 Manne, V., et al. 1995. Drug Development Res. 34, 121.
    Patel, D.V., et al. 1995. J. Med. Chem. 38, 2906.
    产品信息
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₉H₂₉NO₆P · 3Na
    化学配方 C₁₉H₂₉NO₆P · 3Na
    Molar Mass 467.4
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 Farnesyltransferase (Ftase)
    主靶IC50 83 nM against Ftase
    纯度 ≥85% by NMR
    理化信息
    细胞可渗透 N
    溶解度 H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 ≤ -70°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 4 months at -70°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,344150,FPT Inhibitor I - Calbiochem

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