- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
经验配方 CAS号 C₁₅H₁₃FO₂ 5104-49-4 描述 概述 A mixture of S(+) and R(–) enantiomers. A cell-permeable, non-steroidal anti-inflammatory agent that acts as a potent inhibitor of cyclooxygenase (IC50 = 5 nM for LPS-induced COX in human peripheral blood cells). Strongly inhibits insoluble transthyretin (TTR) amyloid fibril formation. Suppresses iNOS expression in RAW 264.7 macrophages. Reduces microglial activation and β-amyloid deposit in APP+PS1 transgenic mice. 产品目录编号 344079 品牌系列 Calbiochem®
同义词 (±)-2-Fluoro-α-methyl[1,1ʹ-biphenyl]-4-acetic Acid, U-27182 参考 参考 Jantzen, P.T., et al. 2002. J. Neurosci. 22, 2246.
Hinz, R., et al. 2001. Pharmacol. Res. 18, 151.
Klabunde, T., et al. 2000. Nat. Struct. Biol. 7, 312.
Range, S.P., et al. 2000. Eur. Respir. J. 15, 751.
van Haeringen, N.J., et al. 2000. J. Ocul. Pharmacol. Ther. 16, 353.
Curnock, A.P., et al. 1997. J. Pharmacol. Exp. Ther. 282, 339.
Reindeau, D., et al. 1997. Can. J. Physiol. Pharmacol. 75, 1088.
Wechter, W.J., et al. 1997. Cancer Res. 57, 4316.
Karmali, R.A., and Marsh, J. 1986. Prostaglandins Leukot. Med. 23, 11.
Karmali, R.A., and Marsh, J. 1985. Prostaglandins Leukot. Med. 20, 283.产品信息 CAS号 5104-49-4 具有ATP竞争性 N 形式 White solid Hill配方 C₁₅H₁₃FO₂ 化学配方 C₁₅H₁₃FO₂ Molar Mass 244.3 可逆 N 结构配方图像 生物信息 主靶 Cyclooxygenase 主靶IC50 5 nM for LPS-induced COX 纯度 ≥98% by titration 理化信息 细胞可渗透 Y 溶解度 DMSO GHS安全信息 RTECS DU8341000 安全信息 R相 R: 25
Toxic if swallowed.S相 S: 36/37/39-45
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).储存和货运信息 货运代码 Ambient Temperature Only
毒性 Toxic & Carcinogenic / Teratogenic
有害材料注意事项： Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存 +15°C to +30°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 6 months at 4°C. Further dilution of stock solution in aqueous medium should be made just prior to use.
上一件merck millipore产品：merck millipore,默克密理博,MABS95,Anti-Wnt-1 Antibody, clone 20C3.1
下一件merck millipore产品：merck millipore,默克密理博,ECM554,QCM ECMatrix Cell Invasion Assay, 24-well (8 µm), fluorimetric
相关产品
![merck millipore,默克密理博,344273,Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride - CAS 115116-37-5 - Calbiochem](/e/upload/m_pic/344273%5B344273-ALL%5D.jpg "merck millipore,默克密理博,344273,Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride - CAS 115116-37-5 - Calbiochem")
merck millipore,默克密理博,14-448M,Cdk2/Cyclin A Protein, active, 250 µg
merck millipore,默克密理博,MABS95,Anti-Wnt-1 Antibody, clone 20C3.1
merck millipore,默克密理博,ECM554,QCM ECMatrix Cell Invasion Assay, 24-well (8 µm), fluorimetric
merck millipore,默克密理博,ABS479,Anti-STAR Antibody
merck millipore,默克密理博,20-160,1M Tris-HCl, pH 6.5
merck millipore,默克密理博,14-803M,Insulin Receptor, activated, 250 µg
