- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 可用的分析物 检测方法 M, H KA PI 3-Kinase HTRF 描述 产品目录编号 33-040 品牌系列 Upstate
商名 - Upstate
- HTRF
描述 PI 3-Kinase 3-step HTRF™ Assay 产品信息 部件 - Stop Reagent
- 4X Reaction Buffer
- PIP2 (substrate, 1mM stock)
- DM A Reaction Buffer
- DM B Reaction Buffer
- DM C Reaction Buffer
- BPIP3
检测方法 HTRF 应用 应用 Everything you need to perform the PI3 Kinase 3-step HTRF assays (384 wells). 主要应用 - Kinase Assay
生物信息 品种反应性 MouseHuman 可用的分析物 - PI 3-Kinase
Entrez基因编号 - NM_006218.2
Entrez基因汇总 Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. 基因符号 - p110-alpha
- PIK3CA
- MGC142163
- PI3K
- MGC142161
靶子系列 PI3K/PI4K UniProt编号 - P42336
UniProt汇总 FUNCTION: SwissProt: P42336 # Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2.
SIZE: 1068 amino acids; 124284 Da
SUBUNIT: Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit. Binds to IRS1 in nuclear extracts. Interacts with RUFY3 (By similarity).
DISEASE: SwissProt: P42336 # Defects in PIK3CA are associated with colorectal cancer (CRC) [MIM:114500]. & Defects in PIK3CA are associated with breast cancer [MIM:114480]. & Defects in PIK3CA are associated with epithelial ovarian cancer (EOC) [MIM:604370].
SIMILARITY: SwissProt: P42336 ## Belongs to the PI3/PI4-kinase family. & Contains 1 C2 domain. & Contains 1 PI3K/PI4K domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 12 months at -70°C 包装信息 数量 384 wells 包装 Kit capacity: 384 wells
上一件merck millipore产品：merck millipore,默克密理博,ECM610,PAI Activity Assay
下一件merck millipore产品：merck millipore,默克密理博,ABN476,Anti-ACVR1C Antibody
相关产品
merck millipore,默克密理博,AP183C,Goat Anti-Rat IgG Antibody, Cy3 conjugate, Species Adsorbed
merck millipore,默克密理博,GF310,PDGF-BB Protein, Human Recombinant Animal Free
merck millipore,默克密理博,AB1690,Anti-Ubiquitin Antibody
merck millipore,默克密理博,ECM610,PAI Activity Assay
merck millipore,默克密理博,ABN476,Anti-ACVR1C Antibody
merck millipore,默克密理博,12-358,Acetyl-Histone H3 (Lys9) Peptide
merck millipore,默克密理博,SCM102,Cardiomyocyte Differentiation Medium
merck millipore,默克密理博,559404,SB 239063 - CAS 798558-40-4 - Calbiochem