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merck millipore,默克密理博,324897,InSolution™ eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem
产品名称：InSolution™ eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem
产品型号：324897
The InSolution™ eIF-2α Inhibitor, Salubrinal, also referenced under CAS 304475-63-6, controls the biological activity of eIF-2α. This small molecule/inhibitor is primarily used for Phosphorylation & D More>>
merck millipore,默克密理博,324897,InSolution™ eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem
- 产品介绍
- merck millipore,默克密理博,324897,InSolution™ eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem
重要规格表
经验配方 CAS号 C₂₁H₁₇Cl₃N₄OS 304475-63-6 描述 概述 A cell-permeable and selective inhibitor of the phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF-2α). Shown to offer protection against ER stress-induced apoptosis (EC50 ~15 µM in PC12 cells stimulated with 750 ng/ml of Tunicamycin (Cat. No. 654380). Prevents HSV replication both in Vero cells (IC50 ~3 µM for reducing plaque formation) in vitro and in a mouse cornea infection model in vivo. The solid form of this compound (Cat. No. 324895) is also available. 产品目录编号 324897 品牌系列 Calbiochem®
同义词 N-(2,2,2-Tichloro-1-(3-quinolin-8-ylthioureido)ethyl)cinnamamide 参考 参考 Boyce, M., et al. 2005. Science 307, 935. 产品信息 CAS号 304475-63-6 形式 Liquid 配方 A 50 mM (5 mg/208 µL) solution of eIF-2α Inhibitor, Salubrinal (Cat. No. 324895) in DMSO. Hill配方 C₂₁H₁₇Cl₃N₄OS Molar Mass 479.8 吸湿 Hygroscopic
结构配方图像 生物信息 主靶 eIF-2α 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 安全信息 R相 R: 36/38
Irritating to eyes and skin.S相 S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.储存和货运信息 货运代码 Dry Ice Only
毒性 Irritant
储存 ≤ -70°C
避光 Protect from light
吸湿 Hygroscopic
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C. 包装信息 惰性气体下包装 Packaged under inert gas
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