merck millipore,默克密理愽
  • merck millipore,默克密理博,324881,PERK, GST-Fusion, Human, Recombinant, E. coli

  • merck millipore,默克密理博,324881,PERK, GST-Fusion, Human, Recombinant, E. coli

    产品名称：PERK, GST-Fusion, Human, Recombinant, E. coli
    产品型号：324881


    merck millipore,默克密理博,324881,PERK, GST-Fusion, Human, Recombinant, E. coli

  • 产品介绍
  • merck millipore,默克密理博,324881,PERK, GST-Fusion, Human, Recombinant, E. coli

    描述
    概述 Recombinant, human PERK consisting of amino acids 563-1115 fused at the N-terminus to GST and expressed in E. coli. PERK phosphorylates the α-subunit of eukaryotic translation initiation factor 2 (EIF2α), which leads to its inactivation and reduces translation initiation. The active kinase is useful for the study of PERK regulation and for inhibitor screening.
    Note: the calculated MW is 88,000, but the protein runs at ~115,000 on SDS-PAGE.
    产品目录编号 324881
    品牌系列 Calbiochem®
    同义词 EIF2AK3 PKR
    应用数据
    The activity of PERK was measured as outlined in the Recommended Reaction Conditions.
    参考
    参考 Baltzis, D., et al. 2007. J Biol Chem. 43, 31675.
    Koumenis, C., et al. 2002. Mol Cell Biol. 21, 7405.
    产品信息
    形式 Liquid
    配方 In 50 mM Tris-HCl, 50 mM NaCl, 250 µM DTT, 100 µM EGTA, 100 µM EDTA, 100 µM PMSF, 25% glycerol, pH 7.5.
    Molar Mass 115000
    生物信息
    纯度 ≥90% by SDS-PAGE
    特异活性 ≥26 nmol/min/mg protein
    浓缩标签 Please refer to vial label for lot-specific concentration
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Standard Handling
    储存 ≤ -70°C
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C).

    merck millipore,默克密理博,324881,PERK, GST-Fusion, Human, Recombinant, E. coli

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