merck millipore,默克密理愽
  • merck millipore,默克密理博,324414,Dynamin Inhibitor V, 34-2 - Calbiochem

  • merck millipore,默克密理博,324414,Dynamin Inhibitor V, 34-2 - Calbiochem

    产品名称：Dynamin Inhibitor V, 34-2 - Calbiochem
    产品型号：324414
    The Dynamin Inhibitor V, 34-2 controls the biological activity of Dynamin. This small molecule/inhibitor is primarily used for Membrane applications.

    merck millipore,默克密理博,324414,Dynamin Inhibitor V, 34-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,324414,Dynamin Inhibitor V, 34-2 - Calbiochem

    重要规格表

    经验配方
    C₂₅H₃₆N₄O
    描述
    概述 A cell-permeable, allosteric Dynamin inhibitor (IC50 = 6.9 µM and 14 µM for full length Dynamin I and Dynamin II GTPase activity, respectively, in vitro). 10 µM of this compound results in cytokinesis failure at the abscission stage in HeLa cultures, with 82% of cells that enter into mitosis becoming multinucleated, and with 97% resulting in cell death. However, it displays a much reduced effect in NIH3T3 cells at the same concentration. It elicits a dose-dependent reduction in cell growth against SMA-560, SJ-G2, SW480, MCF-7 and A2780 cultures, as being the most sensitive among a panel of other cancer cell lines (GI50 = 4.0–37 µM). It was further shown to be 6-fold more active (IC50 = 5.0 µM) than dynamin mediated receptor mediated endocytosis (RME) in U2OS cells, and 15-fold more active (IC50 = 1.3 µM) than Dynasore (Cat. No. 324410) in another Dynamin I GTPase activity assay.
    产品目录编号 324414
    品牌系列 Calbiochem®
    同义词 2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-indol-3-yl)-acrylamide
    参考
    参考 Chircop, M. et al. 2011. Mol. Cancer Ther. 10, 1553.
    Hill, T.A., et al. 2009. J. Med. Chem. 52, 3762.
    产品信息
    形式 Yellow solid
    Hill配方 C₂₅H₃₆N₄O
    化学配方 C₂₅H₃₆N₄O
    Molar Mass 408.6
    结构配方图像
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,324414,Dynamin Inhibitor V, 34-2 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,MAFBN0B50,Multiscreen GFB Filter Plate, Opaque Non-sterile
下一件merck millipore产品：merck millipore,默克密理博,04-387,Anti-TBK1/NAK (NT) Antibody, clone EP611Y, rabbit monoclonal


相关产品

merck millipore,默克密理博,25-006,p53 Activating Ligand merck millipore,默克密理博,25-006,p53 Activating Ligand

merck millipore,默克密理博,108320,N-[叁(羟甲)甲基]-3-胺丙烷磺酸 merck millipore,默克密理博,108320,N-[叁(羟甲)甲基]-3-胺丙烷磺酸

merck millipore,默克密理博,MAB1271,Anti-Golgi Zone Antibody, clone 371-4 merck millipore,默克密理博,MAB1271,Anti-Golgi Zone Antibody, clone 371-4

merck millipore,默克密理博,AB3503-I,Anti-PDX-1 Antibody merck millipore,默克密理博,AB3503-I,Anti-PDX-1 Antibody

merck millipore,默克密理博,MAFBN0B50,Multiscreen GFB Filter Plate, Opaque Non-sterile merck millipore,默克密理博,MAFBN0B50,Multiscreen GFB Filter Plate, Opaque Non-sterile

merck millipore,默克密理博,04-387,Anti-TBK1/NAK (NT) Antibody, clone EP611Y, rabbit monoclonal merck millipore,默克密理博,04-387,Anti-TBK1/NAK (NT) Antibody, clone EP611Y, rabbit monoclonal

merck millipore,默克密理博,MABC39,Anti-LAMP-1 (CD107a) Antibody, clone 1D4B merck millipore,默克密理博,MABC39,Anti-LAMP-1 (CD107a) Antibody, clone 1D4B

merck millipore,默克密理博,HTS204M,ChemiSCREEN™ Membrane Preparation Recombinant Human Y4 Neuropeptide Y Receptor merck millipore,默克密理博,HTS204M,ChemiSCREEN™ Membrane Preparation Recombinant Human Y4 Neuropeptide Y Rec...

merck millipore,默克密理博,AB6014,Anti-MMP-9 Antibody, CT merck millipore,默克密理博,AB6014,Anti-MMP-9 Antibody, CT

merck millipore,默克密理博,MAB13426,Anti-MMP-13 Antibody, clone LIPCO IID1 merck millipore,默克密理博,MAB13426,Anti-MMP-13 Antibody, clone LIPCO IID1


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部