merck millipore,默克密理博,04-387,Anti-TBK1/NAK (NT) Antibody, clone EP611Y, rabbit monoclonal

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merck millipore,默克密理博,04-387,Anti-TBK1/NAK (NT) Antibody, clone EP611Y, rabbit monoclonal
产品名称：Anti-TBK1/NAK (NT) Antibody, clone EP611Y, rabbit monoclonal
产品型号：04-387
Anti-TBK1/NAK (N-term) Antibody, clone EP611Y, Rabbit Monoclonal is an antibody against TBK1/NAK (N-term) for use in Western Blotting, ICC, Immunoprecipitation, IHC(P). Less<<

merck millipore,默克密理博,04-387,Anti-TBK1/NAK (NT) Antibody, clone EP611Y, rabbit monoclonal

产品介绍

merck millipore,默克密理博,04-387,Anti-TBK1/NAK (NT) Antibody, clone EP611Y, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	ICC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	04-387
描述	Anti-TBK1/NAK (NT) Antibody, clone EP611Y, rabbit monoclonal
Alternate Names	serine/threonine-protein kinase TBK1 TANK-binding kinase 1 NF-kappa-B-activating kinase NF-kB-activating kinase
背景信息	NFkappaB-activating kinase (NAK) also known as TANK binding kinase-1 (TBK1) or tumor necrosis factor receptor associated factor 2-associated kinase (T2K) is a serine/threonine protein that belongs to the IkB kinase (IKK) family (1). Similar to IKK alpha and beta (2), NAK induces IkB degradation and NF-kB activity. NAK is activated by phorbol ester tumor promoters and growth factors, whereas catalytically inactive NAK specifically inhibits activation of NF-kB by protein kinase C-epsilon (PKCepsilon). NAK specifically phosphorylates IkB alpha on Serine 36 and NFkB subunit RelA (p65) on Serine 536 (3). NAK is also known to interact with TANK, TRAF-2 and TRIF (4).

产品信息
格式	Unpurified
控制	HeLa cell lysate
演示	Rabbit Monoclonal in buffer containing glycerol, BSA, and sodium azide.

应用
应用	Anti-TBK1/NAK (N-term) Antibody, clone EP611Y, Rabbit Monoclonal is an antibody against TBK1/NAK (N-term) for use in Western Blotting, ICC, Immunoprecipitation, IHC(P).
主要应用	Immunocytochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:50 dilution from a representative lot was used in human breast carcinoma tissue. Immunocytochemistry Analysis: A 1:250-500 dilution from a representative lot was used in IC. Immunoprecipitation Analysis: A 1:10-100 dilution from a representative lot was used in IP.

生物信息
免疫原品种	Synthetic peptide corresponding to the N-terminus of human TBK1/NAK.
表位	N-terminus
克隆	EP611Y
宿主	Rabbit
特异性	This antibody recognizes the N-terminus of TBK1/NAK.
同种型	IgG
品种反应性	RatHumanMouse
Species Reactivity Note	Demonstrated to react with Human, Mouse and Rat.
抗体类型	Monoclonal Antibody
Entrez基因编号	Q9UHD2
基因符号	EC 2.7.11 NAK T2K FLJ11330 OTTHUMP00000239491 EC 2.7.11.1
纯化方法	Unpurified
UniProt编号	Q9UHD2

产品使用声明
质量保证	Evaluated by Western Blot in HeLa cell lysate WesternBlot Analysis: A 1:1,000 dilution of this antibody detected TBK1/NAK in HeLa cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20ºC. Avoid freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20ºC from date of receipt.
Handling Recommendations: Upon first thaw, and prior to removing cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20ºC. Avoid freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.