merck millipore,默克密理愽
  • merck millipore,默克密理博,260960,DNA-PK Inhibitor - CAS 20357-25-9 - Calbiochem

  • merck millipore,默克密理博,260960,DNA-PK Inhibitor - CAS 20357-25-9 - Calbiochem

    产品名称：DNA-PK Inhibitor - CAS 20357-25-9 - Calbiochem
    产品型号：260960
    The DNA-PK Inhibitor, also referenced under CAS 20357-25-9, controls the biological activity of DNA-PK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicat More>>

    merck millipore,默克密理博,260960,DNA-PK Inhibitor - CAS 20357-25-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,260960,DNA-PK Inhibitor - CAS 20357-25-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₉H₉NO₅20357-25-9
    描述
    概述 A cell-permeable vanillin derivative that acts as a potent and selective inhibitor of DNA-PK (DNA-dependent protein kinase) activity (IC50 = 15 µM) and DNA-PK-mediated DSB (double strand break) DNA repair by NHEJ (non-homologous DNA-end-joining). Shown to effectively sensitize cells to killing by Cisplatin (Cat. No. 232120). Does not affect PKC or Chk2 kinase activities.
    产品目录编号 260960
    品牌系列 Calbiochem®
    同义词 DMNB, 4,5-Dimethoxy-2-nitrobenzaldehyde, DNA-Dependent Protein Kinase Inhibitor
    参考
    参考 Willmore, E., et al. 2004. Blood,103, 4659.
    Durant, S., and Karran, P. 2003. Nucleic Acids Res. 31, 5501.
    产品信息
    CAS号 20357-25-9
    具有ATP竞争性 N
    形式 Bright Yellow solid
    Hill配方 C₉H₉NO₅
    化学配方 C₉H₉NO₅
    Molar Mass 211.2
    可逆 N
    结构配方图像
    生物信息
    主靶 DNA-PK activity
    主靶IC50 15 µM against DNA-PK (DNA-dependent protein kinase) activity
    纯度 ≥90% by GC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Carcinogenic / Teratogenic
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,260960,DNA-PK Inhibitor - CAS 20357-25-9 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,20-156,LiCl Immune Complex Wash Buffer


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