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merck millipore,默克密理博,260920,DNA Methyltransferase Inhibitor - CAS 32675-71-1 - Calbiochem
产品名称:DNA Methyltransferase Inhibitor - CAS 32675-71-1 - Calbiochem
产品型号:260920
The DNA Methyltransferase Inhibitor, also referenced under CAS 32675-71-1, controls the biological activity of DNA Methyltransferase. This small molecule/inhibitor is primarily used for Cell Structure More>>
merck millipore,默克密理博,260920,DNA Methyltransferase Inhibitor - CAS 32675-71-1 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₉H₁₄N₂O₄ 32675-71-1 描述 概述 A cell-permeable, specific DNA methyltransferases inhibitor (IC50 = 115 nM for CpG methylase M.SssI) that displays anti-proliferative, but not cytotoxic, properties. Unlike the commonly used inhibitor 5-azacytidine, RG108 directly interacts with DNA methyltransferase active site via its carboxy group. 产品目录编号 260920 品牌系列 Calbiochem®
同义词 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propionic acid, RG108, DNA MTase Inhibitor I 参考 参考 Brueckner, B., et al. 2005. Cancer Res. 65, 6305. 产品信息 CAS号 32675-71-1 具有ATP竞争性 N 形式 Yellow solid Hill配方 C₁₉H₁₄N₂O₄ 化学配方 C₁₉H₁₄N₂O₄ Molar Mass 334.3 可逆 N 结构配方图像 生物信息 主靶 CPG methylase M.Sssl 主靶IC50 115 nM 纯度 ≥98% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO or MeOH 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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