• merck millipore,默克密理博,260920,DNA Methyltransferase Inhibitor - CAS 32675-71-1 - Calbiochem
  • merck millipore,默克密理博,260920,DNA Methyltransferase Inhibitor - CAS 32675-71-1 - Calbiochem

    产品名称:DNA Methyltransferase Inhibitor - CAS 32675-71-1 - Calbiochem
    产品型号:260920
    The DNA Methyltransferase Inhibitor, also referenced under CAS 32675-71-1, controls the biological activity of DNA Methyltransferase. This small molecule/inhibitor is primarily used for Cell Structure More>>

    merck millipore,默克密理博,260920,DNA Methyltransferase Inhibitor - CAS 32675-71-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,260920,DNA Methyltransferase Inhibitor - CAS 32675-71-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₉H₁₄N₂O₄32675-71-1
    描述
    概述 A cell-permeable, specific DNA methyltransferases inhibitor (IC50 = 115 nM for CpG methylase M.SssI) that displays anti-proliferative, but not cytotoxic, properties. Unlike the commonly used inhibitor 5-azacytidine, RG108 directly interacts with DNA methyltransferase active site via its carboxy group.
    产品目录编号 260920
    品牌系列 Calbiochem®
    同义词 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propionic acid, RG108, DNA MTase Inhibitor I
    参考
    参考 Brueckner, B., et al. 2005. Cancer Res. 65, 6305.
    产品信息
    CAS号 32675-71-1
    具有ATP竞争性 N
    形式 Yellow solid
    Hill配方 C₁₉H₁₄N₂O₄
    化学配方 C₁₉H₁₄N₂O₄
    Molar Mass 334.3
    可逆 N
    结构配方图像
    生物信息
    主靶 CPG methylase M.Sssl
    主靶IC50 115 nM
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or MeOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,260920,DNA Methyltransferase Inhibitor - CAS 32675-71-1 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,528113,PI 3-Kβ Inhibitor VI, TGX-221 - CAS 663619-89-4 - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,71058,RosettaBlue™ Competent Cells - Novagen



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