merck millipore,默克密理博,250233,Cytochalasin B, Helminthosporium dematioideum - CAS 14930-96-2

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merck millipore,默克密理博,250233,Cytochalasin B, Helminthosporium dematioideum - CAS 14930-96-2 - Calbiochem
产品名称：Cytochalasin B, Helminthosporium dematioideum - CAS 14930-96-2 - Calbiochem
产品型号：250233
Cell-permeable fungal toxin.

merck millipore,默克密理博,250233,Cytochalasin B, Helminthosporium dematioideum - CAS 14930-96-2 - Calbiochem

产品介绍

merck millipore,默克密理博,250233,Cytochalasin B, Helminthosporium dematioideum - CAS 14930-96-2 - Calbiochem

重要规格表

经验配方	CAS号
C₂₉H₃₇NO₅	14930-96-2

描述
概述	Cell-permeable fungal toxin. Inhibits cytoplasmic division by blocking the formation of contractile microfilaments. Inhibits cell movement and induces nuclear extrusion. Shortens actin filaments by blocking monomer addition at the fast-growing end of polymers. Inhibits glucose transport and platelet aggregation. Blocks adenosine-induced apoptotic body formation without affecting activation of endogenous ADP-ribosylation in leukemia HL-60 cells.
产品目录编号	250233
品牌系列	Calbiochem®

参考
参考	Tanaka, Y., et al. 1994. Exp. Cell Res. 213, 242. Theodoropoulos, P.A., et al. 1994. Biochem. Pharmacol. 47, 1875. Benya, P.D., and Padilla, S.R. 1993. Exp. Cell Res. 204, 268. Cairns, M.T., et al. 1991. J. Biol. Chem. 266, 8176. Nowak, D. 1990. Biomed. Biochim. Acta 49, 353. Wang, F., et al. 1990. Biochem. Biophys. Res. Commun. 171, 543. Edwards, S.W., and Lloyd, D. 1988. FEBS Lett. 227, 39.

参考

Tanaka, Y., et al. 1994. Exp. Cell Res. 213, 242.
Theodoropoulos, P.A., et al. 1994. Biochem. Pharmacol. 47, 1875.
Benya, P.D., and Padilla, S.R. 1993. Exp. Cell Res. 204, 268.
Cairns, M.T., et al. 1991. J. Biol. Chem. 266, 8176.
Nowak, D. 1990. Biomed. Biochim. Acta 49, 353.
Wang, F., et al. 1990. Biochem. Biophys. Res. Commun. 171, 543.
Edwards, S.W., and Lloyd, D. 1988. FEBS Lett. 227, 39.

产品信息
CAS号	14930-96-2
具有ATP竞争性	N
形式	White solid
Hill配方	C₂₉H₃₇NO₅
化学配方	C₂₉H₃₇NO₅
Molar Mass	479.6
可逆	N
结构配方图像

生物信息
主靶	Blocking the formation of contractile microfilaments
纯度	≥98% by HPLC

理化信息
细胞可渗透	Y
溶解度	MeOH or DMSO

GHS安全信息
RTECS	RO0205000

安全信息
R相	R: 26/27/28-63 Very toxic by inhalation, in contact with skin and if swallowed. Possible risk of harm to the unborn child.
S相	S: 22-36/37/39-45 Do not breathe dust. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Highly Toxic & Carcinogenic / Teratogenic
有害材料注意事项：	Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存	-20°C
避光	Protect from light
无需冷冻	No
特殊指南	Following reconstitution store in the refrigerator (4°C). Stock solutions are stable for up to 3 months at 4°C.