merck millipore,默克密理愽
  • merck millipore,默克密理博,23-056M,XIAP, active

  • merck millipore,默克密理博,23-056M,XIAP, active

    产品名称：XIAP, active
    产品型号：23-056M


    merck millipore,默克密理博,23-056M,XIAP, active

  • 产品介绍
  • merck millipore,默克密理博,23-056M,XIAP, active

    描述
    产品目录编号 23-056M
    品牌系列 Upstate
    商名
    • Upstate
    描述 XIAP, active
    长描述 N-terminal GST-tagged, recombinant human XIAP full length, expressed by baculovirus in Sf21 insect cells
    Alternate Names
    • Inhibitor of apoptosis protein 3 (API3)
    • Baculoviral IAP repeat-containing protein 4 (BIRC4)
    • IAP-like protein
    背景信息 X-linked inhibitor of apoptosis (XIAP) is one of a group of intracellular proteins which have been shown to act as endogenous inhibitors of caspases, the enzymatic effectors of apoptosis. XIAP possesses a C-terminal RING domain that functions as an E3 ubiquitin ligase and is able to ubiquitinate a variety of substrates thereby affecting a broad range of cellular activities beyond apoptotic suppression. There is evidence that XIAP plays a significant role in cell division, morphogenesis, heavy metal homeostasis, NF-kB activation and MAP kinase signalling. XIAP expression has been shown to be elevated in several malignancies and so is considered a promising target in anticancer therapies.
    应用
    主要应用
    • Enzyme Assay
    生物信息
    品种 Human
    级联部件 E3
    Entrez基因编号
    • NM_001167
    纯化方法 Purified using glutathione sepharose, followed by gel filtration
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    包装信息
    数量 250 µg

    merck millipore,默克密理博,23-056M,XIAP, active

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