• merck millipore,默克密理博,23-048M,Parkin Protein, active, 250 µg
  • merck millipore,默克密理博,23-048M,Parkin Protein, active, 250 µg

    产品名称:Parkin Protein, active, 250 µg
    产品型号:23-048M
    Active, full length, human recombinant human Parkin. N-terminal 6His-tagged. For use in Enzyme Assays. Functions as an E3 ligase in ubiquitination assays.

    merck millipore,默克密理博,23-048M,Parkin Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,23-048M,Parkin Protein, active, 250 µg

    重要规格表

    主要应用 品种 级联部件
    EAHumanE3
    描述
    产品目录编号 23-048M
    品牌系列 Upstate
    商名
    • Upstate
    描述 Parkin Protein, active, 250 µg
    长描述 N-terminal 6His-tagged, recombinant human Parkin full length, expressed by baculovirus in Sf21 insect cells. Purified using immobilized metal affinity chromatography.
    Alternate Names
    • PRKN
    • Parkinson juvenile disease protein 2
    • PARK2
    背景信息 Parkin is an E3-ubiquitin ligase belonging to the RBR (RING – In Between RING – RING) family. Mutations in Parkin that result in a loss-of-function are the most frequent cause of familial Parkinson’s disease and are responsible for a large percentage of autosomal recessive juvenile parkinsonism (AR-JP). In addition to its auto-ubiquitination, Parkin can also ubiquitinate various substrates, including the CDK2-interacting protein cyclin E1, the -synuclein-interacting protein synphilin-1, the synaptic vesicle-associated CDC-rel1 and the p38 subunit of aminoacyl-tRNA synthetase/JTV-1. Ubiquitination of substrates occurs in conjunction with the E2 enzymes UbcH7, UbcH8 or UbcH13/Uev1.
    应用
    应用 Active, full length, human recombinant human Parkin. N-terminal 6His-tagged. For use in Enzyme Assays. Functions as an E3 ligase in ubiquitination assays.
    主要应用
    • Enzyme Assay
    生物信息
    品种 Human
    级联部件 E3
    Entrez基因编号
    • GenBank NM_004562
    纯化方法 Purified using immobilized metal affinity chromatography.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    包装信息
    数量 250 µg

    merck millipore,默克密理博,23-048M,Parkin Protein, active, 250 µg

上一件merck millipore产品:merck millipore,默克密理博,AP136A,Goat Anti-Rat IgG Antibody, Alkaline Phosphatase conjugate
下一件merck millipore产品:merck millipore,默克密理博,14-582M,FGFR1 Protein, active, 250 µg



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