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merck millipore,默克密理博,23-036,UbcH6 Protein, active, 10 µg
产品名称:UbcH6 Protein, active, 10 µg
产品型号:23-036
Active, full length, recombinant human UbcH6. N-terminal HA, 6His-tagged. For use in Enzyme Assays. Functions as an E2 enzyme in ubiquitination assays.
merck millipore,默克密理博,23-036,UbcH6 Protein, active, 10 µg
- 产品介绍
重要规格表
主要应用 品种 级联部件 EA Human E2 描述 产品目录编号 23-036 品牌系列 Upstate
商名 - Upstate
描述 UbcH6 Protein, active, 10 µg 长描述 N-terminal HA, 6His-tagged, recombinant human UbcH6 full length, expressed in E.coli Alternate Names - UBE2E1
- Ubiquitin-conjugating enzyme E2 E1
- Ubiquitin-protein ligase E1
背景信息 Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site residue. E2 enzymes act via selective protein-protein interactions with the ubiquitin-activating E1 enzyme and ubiquitin ligase E3 enzymes and are able to differentiate effects on downstream substrates, either with a single Ub molecule or a Ub chain. While E3s are involved in substrate selection, E2s are the main determinants for selection of the lysine to construct Ub chains, which thereby directly control the cellular fate of the substrate.
UbcH6 has been shown to interact with a number of diverse E3 ligases, including RNF20/40, Trim32 and WWP2.应用 应用 Active, full length, recombinant human UbcH6. N-terminal HA, 6His-tagged. For use in Enzyme Assays. Functions as an E2 enzyme in ubiquitination assays. 主要应用 - Enzyme Assay
生物信息 品种 Human 级联部件 E2 Entrez基因编号 - NM_003341
纯化方法 Purified using immobilized metal affinity chromatography. UniProt编号 - P51965
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 10 µg
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