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merck millipore,默克密理博,219360,Cathepsin D/E Substrate, Fluorogenic - Calbiochem
产品名称：Cathepsin D/E Substrate, Fluorogenic - Calbiochem
产品型号：219360
An internally quenched fluorogenic 11-mer peptide that acts as a sensitive and selective substrate for cathepsins D and E, but not cathepsins B, H, or L .
merck millipore,默克密理博,219360,Cathepsin D/E Substrate, Fluorogenic - Calbiochem
- 产品介绍
重要规格表
描述 概述 An internally quenched fluorogenic 11-mer peptide that acts as a sensitive and selective substrate for cathepsins D and E (kcat/Km = 15.6 µM-1s-1 and 10.9 µM-1s-1 for rat gastric cathepsin D and human erythrocyte cathepsin E, respectively), but not cathepsins B, H, or L . Cleavage occurs between Phe-Phe residues and results in enhanced fluorescence. A useful tool for inhibitors screening or for the determination of cathepsins D and E activities in crude extracts of various tissues and cell lysates. 产品目录编号 219360 品牌系列 Calbiochem®
同义词 MOCAc-GKPILF~FRLK(Dnp)-D-R-NH₂ 参考 参考 Yasuda, Y., et al. 1999. J. Biochem. 126, 260.
Yasuda, Y., et al. 1999. J. Biochem. 125, 1137.产品信息 具有ATP竞争性 N 形式 Yellow lyophilized solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₈₅H₁₂₂N₂₂O₁₉ 化学配方 C₈₅H₁₂₂N₂₂O₁₉ Molar Mass 1756 吸湿 Hygroscopic
肽序列 MOCAc-Gly-Lys-Pro-Ile-Leu-Phe~Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH₂
MOCAc = (7-Methoxycoumarin-4-yl)acetyl
可逆 N 生物信息 主靶 Substrate for cathepsins D and E 主靶IC50 kcat/Km = 15.6 µM⁻¹ sec⁻¹ and 10.9 µM⁻¹ sec⁻¹ for rat gastric cathepsin D and human erythrocyte cathepsin E, respectively 纯度 ≥97% by HPLC 理化信息 细胞可渗透 N 最大排放 ~393 nm 最大激励 ~328 nm 溶解度 DMSO 肽序列 MOCAc-Gly-Lys-Pro-Ile-Leu-Phe~Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH₂
MOCAc = (7-Methoxycoumarin-4-yl)acetyl
储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
上一件merck millipore产品：merck millipore,默克密理博,584223,InSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,71207,(DE3) Competent Cell Set 1 - Novagen
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