• merck millipore,默克密理博,218718,Casein Kinase II Inhibitor VI, TMCB - CAS 905105-89-7 - Calbiochem
  • merck millipore,默克密理博,218718,Casein Kinase II Inhibitor VI, TMCB - CAS 905105-89-7 - Calbiochem

    产品名称:Casein Kinase II Inhibitor VI, TMCB - CAS 905105-89-7 - Calbiochem
    产品型号:218718
    The Casein Kinase II Inhibitor VI, TMCB, also referenced under CAS 905105-89-7, controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylatio More>>

    merck millipore,默克密理博,218718,Casein Kinase II Inhibitor VI, TMCB - CAS 905105-89-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,218718,Casein Kinase II Inhibitor VI, TMCB - CAS 905105-89-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₁H₉Br₄N₃O₂905105-89-7
    描述
    概述 A cell-permeable tertabromobenzimidazolo TBB (Cat. Nos. 218699 and 218708) analog that acts as a highly selective (IC50 >10 µM against 71 other kinases) ATP-competitive inhibitor against CK2 (IC50 = 500 nM; Ki = 250 nM) and ERK8 (IC50 = 500 nM). K66 is reported to be more selective than either TBB or DMAT and selective CK2 inhibition by K66 is shown to be cytotoxic to non-ERK8-expressing Jurkat cells.
    产品目录编号 218718
    品牌系列 Calbiochem®
    同义词 ERK8 Inhibitor I, 4,5,6,7-Tetrabromo-2-dimethylamino-1-carboxymethyl-benzimidazole, K66, Erk Inhibitor VI
    参考
    参考 Pagano, M.A., et al. 2008. Biochem. J. 415, 353.
    产品信息
    CAS号 905105-89-7
    形式 White powder
    Hill配方 C₁₁H₉Br₄N₃O₂
    化学配方 C₁₁H₉Br₄N₃O₂
    Molar Mass 534.8
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO
    安全信息
    R相 R: 36/37/38

    Irritating to eyes, respiratory system and skin.
    S相 S: 26-36

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,218718,Casein Kinase II Inhibitor VI, TMCB - CAS 905105-89-7 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,211875,Captopril - CAS 62571-86-2 - Calbiochem
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