merck millipore,默克密理愽
  • merck millipore,默克密理博,14-766,Tie2 (Y1108F) Protein, active, 10 µg

  • merck millipore,默克密理博,14-766,Tie2 (Y1108F) Protein, active, 10 µg

    产品名称：Tie2 (Y1108F) Protein, active, 10 µg
    产品型号：14-766
    Active, N-terminal 6His-tagged recombinant human Tie2 residues 771-end. For use in Kinase Assays.

    merck millipore,默克密理博,14-766,Tie2 (Y1108F) Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-766,Tie2 (Y1108F) Protein, active, 10 µg

    描述
    产品目录编号 14-766
    品牌系列 Upstate
    商名
    • Upstate
    描述 Tie2 (Y1108F) Protein, active, 10 µg
    概述 N-terminal 6His-tagged recombinant human Tie2 residues 771-end.
    背景信息 Tyrosine 1108 has been identified as an autophosphorylation site in human Tie2. The Y1106F substitution in murine Tie2 (analogous to Y1108F in human Tie2) has been shown to block cell migration by disrupting binding of Tie2 to the docking protein Dok-R (Jones N., et al., Mol Cell Biol.(2003);23:2658-2668 and Murray B.W., et al., Biochemistry.(2001);40:10243-10253).
    产品信息
    演示 50mM Tris/HCl pH8.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij 35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
    应用
    应用 Active, N-terminal 6His-tagged recombinant human Tie2 residues 771-end. For use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 Expressed by baculovirus in Sf21 insect cell.
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_000459. The recombinant protein contains the amino acid substitutions Q939H and Q940H (native protein coordinates) with respect to GenBank NM_000459, both of these are reported in GenBank BC035514.
    基因符号
    • TIE2
    • TEK
    蛋白靶 Tie2
    纯化方法 Ni2+/NTA-agarose
    靶子系列 TK
    UniProt编号
    • Q02858 (mouse)
    • Q02763
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1)
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store -70°C. For maximum recovery of product, centrifuge original vial prior to removing the cap.
    Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70°C.
    包装信息
    数量 10 µg
    包装 Also available in 250μg size-call for pricing and availability and reference catalog number 14-766M when ordering the 250μg size.

    merck millipore,默克密理博,14-766,Tie2 (Y1108F) Protein, active, 10 µg

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