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merck millipore,默克密理博,211875,Captopril - CAS 62571-86-2 - Calbiochem
产品名称：Captopril - CAS 62571-86-2 - Calbiochem
产品型号：211875
An antihypertensive agent that competitively inhibits angiotensin-converting enzyme (ACE; IC₅₀= 23-35 nM) and acts as a reversible and competitive inhibitor of LTA4 hydrolase (IC₅₀ = 11 µM).
merck millipore,默克密理博,211875,Captopril - CAS 62571-86-2 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₉H₁₅NO₃S 62571-86-2 描述 概述 An antihypertensive agent that competitively inhibits angiotensin-converting enzyme (ACE; IC50= 23-35 nM) and acts as a reversible and competitive inhibitor of LTA4 hydrolase (IC50 = 11 µM). Inhibits angiogenesis and slows the growth of experimental tumors in rats. Reported to inhibit apoptosis in human lung epithelial cells (IC50 = ~ 320 nM). 产品目录编号 211875 品牌系列 Calbiochem®
同义词 [2S]-1-[3-Mercapto-2-methylpropionyl]-L-proline, SQ-14225 参考 参考 Uhal, B.D., et al. 1998. Am. J. Physiol. 275, L1013.
Volpert, O.V., et al. 1996. J. Clin. Invest. 98, 671.
Voors, A.A., et al. 1995. J. Cardiovasc. Risk 2, 413.
Orning, L., et al. 1991. J. Biol. Chem. 266, 16507.
Kostis, J. 1988. Am. Heart J. 116, 1591.产品信息 CAS号 62571-86-2 具有ATP竞争性 N 形式 White to off-white solid Hill配方 C₉H₁₅NO₃S 化学配方 C₉H₁₅NO₃S Molar Mass 217.3 可逆 Y 结构配方图像 生物信息 主靶 ACE 主靶IC50 23-35 nM against angiotensin-converting enzyme (ACE); 11 µM against LTA4 hydrolase; ~ 320 nM inhibiting apoptosis in human lung epithelial cells 纯度 ≥98% by titration 理化信息 细胞可渗透 N 溶解度 H₂O GHS安全信息 RTECS UY0550000 安全信息 R相 R: 63-43
Possible risk of harm to the unborn child.
May cause sensitization by skin contact.S相 S: 22-36
Do not breathe dust.
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Carcinogenic / Teratogenic
储存 +2°C to +8°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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