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经验配方 CAS号 C₆H₁₂N₂O₄Pt 41575-94-4 描述 概述 An analog of Cisplatin (Cat. No. 232120) with reduced nephrotoxicity. Displays potent antitumor activity.
Note: Athough soluble in DMSO, Carboplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Water with or without 5% glucose is recommended for solubilization prior to culture treatment.产品目录编号 216100 品牌系列 Calbiochem®
同义词 cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II), JM-8, Paraplatin 参考 参考 Hall, M.D., et al. 2014. Cancer Res. In press.
Smith, I.E., et al. 1985. Cancer Treat. Rep. 69, 43.
Harland, S.J., et al. 1984. Cancer Res. 44, 1693.产品信息 CAS号 41575-94-4 具有ATP竞争性 N 形式 White solid Hill配方 C₆H₁₂N₂O₄Pt 化学配方 C₆H₁₂N₂O₄Pt Molar Mass 371.3 可逆 N 结构配方图像 生物信息 主靶 Potent antitumor activity 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 H₂O with 5% Glucose GHS安全信息 RTECS TP2300000 安全信息 R相 R: 20/21/22-42/43-46-61
Harmful by inhalation, in contact with skin and if swallowed.
May cause sensitization by inhalation and skin contact.
May cause heritable genetic damage.
May cause harm to the unborn child.S相 S: 22-26-36/37/39-45-53
Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Avoid exposure - obtain special instructions before use.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful & Carcinogenic / Teratogenic
储存 +15°C to +30°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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