merck millipore,默克密理愽
  • merck millipore,默克密理博,208722,Calpain Inhibitor III - CAS 88191-84-8 - Calbiochem

  • merck millipore,默克密理博,208722,Calpain Inhibitor III - CAS 88191-84-8 - Calbiochem

    产品名称：Calpain Inhibitor III - CAS 88191-84-8 - Calbiochem
    产品型号：208722
    The Calpain Inhibitor III, also referenced under CAS 88191-84-8, controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

    merck millipore,默克密理博,208722,Calpain Inhibitor III - CAS 88191-84-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,208722,Calpain Inhibitor III - CAS 88191-84-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₂H₂₆N₂O₄88191-84-8
    描述
    概述 A potent, cell-permeable inhibitor of calpain I and II (Ki = 8 nM). Reduces capsaicin-mediated cell death in cultured dorsal root ganglion. Reported to block A23187-induced suppression of neurite outgrowth in isolated hippocampal pyramidal neurons. Exhibits neuroprotective effect in glutamate-induced toxicity.
    产品目录编号 208722
    品牌系列 Calbiochem®
    同义词 Carbobenzoxy-valinyl-phenylalaninal, MDL 28170
    参考
    参考 Chatterjee, S., et al. 1998. J. Med. Chem. 41, 2663.
    Rami, A., et al. 1997. Neurosci. Res. 27, 93.
    Yamazaki, T., et al. 1997. Biochemistry 36, 8377.
    Klafki, H., et al. 1996. J. Biol. Chem. 271, 28655.
    Chard, P.S., et al. 1995. Neuroscience 65, 1099.
    Song, D.K., et al. 1994. J. Neurosci. Res. 39, 474.
    产品信息
    CAS号 88191-84-8
    具有ATP竞争性 N
    形式 White lyophilized solid
    Hill配方 C₂₂H₂₆N₂O₄
    化学配方 C₂₂H₂₆N₂O₄
    Molar Mass 382.5
    肽序列 Z-Val-Phe-CHO
    可逆 N
    结构配方图像
    生物信息
    主靶 calpain 1, calpain 2
    主靶IC50 8 nM
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    肽序列 Z-Val-Phe-CHO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

    merck millipore,默克密理博,208722,Calpain Inhibitor III - CAS 88191-84-8 - Calbiochem

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