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merck millipore,默克密理博,208721,ALLM - CAS 110115-07-6 - Calbiochem
产品名称：ALLM - CAS 110115-07-6 - Calbiochem
产品型号：208721
Cell permeable inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 600 pM).
merck millipore,默克密理博,208721,ALLM - CAS 110115-07-6 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₉H₃₅N₃O₄S 110115-07-6 描述 概述 Cell permeable inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 600 pM). Inhibits activation-induced programmed cell death and restores defective immune responses in HIV+ donors. Blocks nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene. A weak inhibitor of proteasome. 产品目录编号 208721 品牌系列 Calbiochem®
同义词 Calpain Inhibitor II 参考 参考 Ravid, T., et al. 2000. J. Biol. Chem. 275, 35840.
Griscavage, J.M., et al. 1995. Biochem. Biophys. Res. Commun. 215, 721.
Sarin, A., et al. 1994. J. Immunol. 153, 862.
Sarin, A., et al. 1993. J. Exp. Med. 178, 1693.
Banik, N.L., et al. 1992. Neurochem. Res. 17, 797.
Koohmaraie, M. 1992. Biochemie 74, 239.
Pinter, M., et al. 1992. Biochemistry 31, 8201.
Shenoy, A.M., and Brahmi, Z. 1991. Cell. Immunol. 138, 24.
Sasaki, T., et al. 1990. J. Enzyme Inhib. 3, 195.产品信息 CAS号 110115-07-6 具有ATP竞争性 N 形式 Off-white solid Hill配方 C₁₉H₃₅N₃O₄S 化学配方 C₁₉H₃₅N₃O₄S Molar Mass 401.6 肽序列 N-Acetyl-Leu-Leu-Met 可逆 N 结构配方图像 生物信息 主靶 calpain-1 主靶Ki 120 nM, 230 nM, 100 nM, and 600 pM, against calpain I, calpain II, cathepsin B, and cathepsin L, respectively 纯度 >95% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO, MeOH or EtOH 肽序列 N-Acetyl-Leu-Leu-Met 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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