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merck millipore,默克密理博,MAB1940,Anti-Fibronectin Antibody, cellular, clone DH1
产品名称：Anti-Fibronectin Antibody, cellular, clone DH1
产品型号：MAB1940
Detect Fibronectin using this Anti-Fibronectin Antibody, cellular, clone DH1 validated for use in WB, IH.
merck millipore,默克密理博,MAB1940,Anti-Fibronectin Antibody, cellular, clone DH1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Rb, Gp, H, R IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MAB1940 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Fibronectin Antibody, cellular, clone DH1 产品信息 格式 Purified 演示 In PBS with 1% BSA and 0.1% sodium azide. 应用 应用 Detect Fibronectin using this Anti-Fibronectin Antibody, cellular, clone DH1 validated for use in WB, IH. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunoblotting at 1:1,000
Indirect immunohistochemistry at 1:200-1:400
A 1-hour fixation with 3-3.5% paraformaldehyde in 0.1 M phosphate buffer pH 7.4 is suggested. Shows some reactivity on paraffin sections depending on fixation conditions and time (Latvala et al., 1996).
Final working dilutions must be determined by end user.生物信息 免疫原品种 Purified fibronectin from Human A8387 fibrosarcoma cells. 表位 cellular 克隆 DH1 宿主 Mouse 特异性 Specific for the extra domain of cellular fibronectin (EDA sequence) and thus recognizes only the cellular fibronectin. 同种型 IgG1 品种反应性 RabbitGuinea PigHumanRat 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_212482.1
- NM_002026.2
- NM_054034.2
- NM_212474.1
- NM_212475.1
- NM_212476.1
- NM_212478.1
Entrez基因汇总 This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. 基因符号 - FINC
- FN1
- DKFZp686H0342
- DKFZp686I1370
- MSF
- CIG
- LETS
- DKFZp686O13149
- FN
- DKFZp686F10164
UniProt编号 - P02751
UniProt汇总 FUNCTION: SwissProt: P02751 # Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Interaction with TNR mediates inhibition of cell adhesion and neurite outgrowth (By similarity).
SIZE: 2386 amino acids; 262607 Da
SUBUNIT: Mostly heterodimers or multimers of alternatively spliced variants, connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Interacts with FBLN1, AMBP, TNR, LGALS3BP and COL13A1.
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
TISSUE SPECIFICITY: Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.DEVELOPMENTAL STAGE: Ugl-Y1, Ugl-Y2 and Ugl-Y3 are present in the urine from 0 to 17 years of age.
PTM: Sulfated.
SIMILARITY: SwissProt: P02751 ## Contains 12 fibronectin type-I domains. & Contains 2 fibronectin type-II domains. & Contains 16 fibronectin type-III domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at +2-8°C for up to 12 months. 包装信息 数量 50 µg
上一件merck millipore产品：merck millipore,默克密理博,208721,ALLM - CAS 110115-07-6 - Calbiochem
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