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- merck millipore,默克密理博,204882,Complement C2, Human
描述 概述 Native, human C2 complement component. Single chain glycoprotein present in normal human serum at concentration of 20 µg/ml. Classical pathway activation results in assembly of the C1,C4b complex on target surfaces. Subsequent to binding of the C4b component to this complex, C2 is cleaved by the activated C1s subcomponent of C1 into C2a, the 63 kDa C-terminal fragment, and C2b, the 30 kDa N-terminal fragment. The smaller C2b fragment is released while the larger C2a fragment remains associated with the C1,C4b complex to form the C4b,C2a classical pathway C3 convertase enzyme. C2 concentration is based on functional activity measurements relative to a normal human serum standard pool. 产品目录编号 204882 品牌系列 Calbiochem®
参考 参考 Attwood, J.T., et al. 2001. Acta Paediatr. 90, 99. 产品信息 活性 ≥4 × 10⁵ C₂H₅0 units/mg; ≥70% of the C2 activity in normal human serum on a mg/mg basis 形式 Liquid 配方 In PBS, pH 6.0. Molar Mass 93000 生物信息 纯度 ≥90% by SDS-PAGE 来源 Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. 浓缩标签 Please refer to vial label for lot-specific concentration
理化信息 污染物 C1, C3, C4, C5, IgG, IgA, IgM, albumin, Factor B, or hemopexin: 储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C).
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