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描述 产品目录编号 14-686 品牌系列 Upstate
商名 - Upstate
描述 LOK Protein, active, 10 µg 概述 N-terminal 6His-tagged, recombinant human LOK amino acids 1-348 应用 应用 Active, N-terminal 6His-tagged, recombinant human LOK amino acids 1-348, for use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 expressed by baculovirus in Sf21 cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_005990.3
Entrez基因汇总 This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. 基因符号 - LOK
- STK10
- PRO2729
蛋白靶 LOK 纯化方法 Ni2+/NTA-agarose 靶子系列 STE UniProt编号 - O94804
UniProt汇总 FUNCTION: SwissProt: O94804 # Can act on substrates such as myelin basic protein and histone 2A on serine and threonine residues (By similarity).
SIZE: 968 amino acids; 112135 Da
TISSUE SPECIFICITY: Expressed predominantly in lymphoid organs.
PTM: Autophosphorylated (By similarity).
SIMILARITY: SwissProt: O94804 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 protein kinase domain.产品使用声明 质量保证 routinely evaluated by phosphorylation of Axltide (Catalog# 12-516) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 stable 6 months at -70°C from date of shipment 包装信息 数量 10 µg
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