merck millipore,默克密理愽
  • merck millipore,默克密理博,20-131,PKC Substrate Cocktail

  • merck millipore,默克密理博,20-131,PKC Substrate Cocktail

    产品名称：PKC Substrate Cocktail
    产品型号：20-131


    merck millipore,默克密理博,20-131,PKC Substrate Cocktail

  • 产品介绍
  • merck millipore,默克密理博,20-131,PKC Substrate Cocktail

    重要规格表

    主要应用
    KA
    描述
    产品目录编号 20-131
    品牌系列 Upstate
    商名
    • Upstate
    描述 PKC Substrate Cocktail
    产品信息
    演示 20mM MOPS, pH 7.2, 25mM β-glycerophosphate, 1mM sodium orthovanadate, 1mM dithiothreitol, 1mM CaCl2.
    应用
    主要应用
    • Kinase Assay
    应用说明 For use as a substrate in PKC kinase assays.
    生物信息
    Entrez基因编号
    • NM_002737.2
    Entrez基因汇总 Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
    基因符号
    • MGC129900
    • PRKCA
    • PKC-A
    • PKCA
    • PRKACA
    • PKC-alpha
    • MGC129901
    • AAG6
    UniProt编号
    • P17252
    UniProt汇总 FUNCTION: SwissProt: P17252 # PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
    COFACTOR: Binds 3 calcium ions per subunit. The ions are bound to the C2 domain (By similarity).
    SIZE: 672 amino acids; 76764 Da
    SUBUNIT: Interacts with CENTA1, CSPG4 and PRKCABP. Binds to SDPR in the presence of phosphatidylserine.
    SIMILARITY: SwissProt: P17252 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 C2 domain. & Contains 2 phorbol-ester/DAG-type zinc fingers. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 Routinely evaluated in a kinase assay.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 1 year at -20°C
    包装信息
    数量 1 mL

    merck millipore,默克密理博,20-131,PKC Substrate Cocktail

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下一件merck millipore产品：merck millipore,默克密理博,04-1122,Anti-MMP-1 Antibody, clone EP1247Y rabbit monoclonal


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