merck millipore,默克密理愽
  • merck millipore,默克密理博,197332,Bcl-2 Inhibitor III, EM20-25 - CAS 141266-44-6 - Calbiochem

  • merck millipore,默克密理博,197332,Bcl-2 Inhibitor III, EM20-25 - CAS 141266-44-6 - Calbiochem

    产品名称：Bcl-2 Inhibitor III, EM20-25 - CAS 141266-44-6 - Calbiochem
    产品型号：197332
    The Bcl-2 Inhibitor III, EM20-25, also referenced under CAS 141266-44-6, controls the biological activity of Bcl-2. This small molecule/inhibitor is primarily used for Activators/Inducers applications More>>

    merck millipore,默克密理博,197332,Bcl-2 Inhibitor III, EM20-25 - CAS 141266-44-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,197332,Bcl-2 Inhibitor III, EM20-25 - CAS 141266-44-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₅H₉ClN₄O₆141266-44-6
    描述
    概述 A cell-permeable pyrimidine-trione compound that sensitizes apoptosis-resistant, Bcl-2-overexpressing leukemic cells to cytotoxic drugs. Shown to bind to Bcl-2, disrupt its interaction with Bax, and activate caspase-9. Also induces PTP (permeability transition pore) opening in both isolated mitochondria and intact cells, without any effect on respiration.
    产品目录编号 197332
    品牌系列 Calbiochem®
    同义词 5-(6-Chloro-2,4-dioxo-1,3,4,10-tetrahydro-2H-9-oxa-1,3-diaza-anthracen-10-yl)-pyrimidine-2,4,6-trione
    参考
    参考 Milanesi, E., et al. 2006. J. Biol. Chem. 281, 10066.
    产品信息
    CAS号 141266-44-6
    具有ATP竞争性 N
    形式 Pale yellow solid
    Hill配方 C₁₅H₉ClN₄O₆
    化学配方 C₁₅H₉ClN₄O₆
    Molar Mass 376.7
    可逆 N
    结构配方图像
    生物信息
    主靶 Bcl-2
    纯度 ≥95% by elemental analysis
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,197332,Bcl-2 Inhibitor III, EM20-25 - CAS 141266-44-6 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,04-797,Anti-phospho-MAP Kinase 1/2 (Erk1/2)(Thr185/Tyr187) Antibody, clone AW39


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