merck millipore,默克密理愽
  • merck millipore,默克密理博,197228,BCRP Inhibitor IV, YHO-13351 - Calbiochem

  • merck millipore,默克密理博,197228,BCRP Inhibitor IV, YHO-13351 - Calbiochem

    产品名称：BCRP Inhibitor IV, YHO-13351 - Calbiochem
    产品型号：197228
    The BCRP Inhibitor IV, YHO-13351 controls the biological activity of BCRP.

    merck millipore,默克密理博,197228,BCRP Inhibitor IV, YHO-13351 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,197228,BCRP Inhibitor IV, YHO-13351 - Calbiochem

    重要规格表

    经验配方
    C₂₆H₃₃N₃O₄S • CH₃SO₃H
    描述
    概述 An in vivo bioavailable (~87%; t1/2 < 5 mins. during p.o. and i.v. administration) and highly water soluble ( >100 mg/ml) diethylaminoacetate prodrug of YHO-13177 (Cat. No. 197227) that reverses BCRP-mediated irinotecan resistance in P388/BCRP and HCT116/BCRP xenograft mouse models, and suppresses tumor growth and significantly enhances the survival (100 or 200 mg/kg, i.p.).
    产品目录编号 197228
    品牌系列 Calbiochem®
    同义词 Diethylaminoacetic acid, 1-(5-((Z)-2-cyano-2- (3,4-dimethoxyphenyl)vinyl)thiophen-2-yl)piperidin-4-yl ester, Methanesulfonate
    参考
    参考 Yamazaki, R., et al. 2011. Mol. Cancer Ther. 10, 1252.
    产品信息
    形式 Yellow solid
    Hill配方 C₂₆H₃₃N₃O₄S • CH₃SO₃H
    化学配方 C₂₆H₃₃N₃O₄S • CH₃SO₃H
    Molar Mass 579.7
    吸湿 Hygroscopic
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 H₂O
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,197228,BCRP Inhibitor IV, YHO-13351 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,528151,InSolution™ PARP Inhibitor VIII, PJ34 - Calbiochem


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