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merck millipore,默克密理博,191501,InSolution™ 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem
产品名称:InSolution™ 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem
产品型号:191501
A Kenpaullone analog that acts as a potent and ATP-competitive inhibitor of GSK-3&beta.
merck millipore,默克密理博,191501,InSolution™ 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₅H₁₀BrN₃O 676596-65-9 描述 概述 A Kenpaullone (Cat. No. 422000) analog that acts as a potent and ATP-competitive inhibitor of GSK-3β (IC50 = 18 nM). Displays over 100-fold greater selectivity over Cdk1/cyclin B and Cdk5/p25 (IC50 = 2.0 µM and 4.2 µM, respectively). The solid form of this compound (Cat. No. 191500) is also available. 产品目录编号 191501 品牌系列 Calbiochem®
参考 参考 Kunick, C., et al. 2004. Bioorg. Med. Chem. Lett. 14, 413. 产品信息 CAS号 676596-65-9 形式 Liquid 配方 A 10 mM (500 µg/152 µL) solution of 1-Azakenpaullone (Cat. No. 191500) in DMSO. Hill配方 C₁₅H₁₀BrN₃O 化学配方 C₁₅H₁₀BrN₃O Molar Mass 328.2 吸湿 Hygroscopic
可逆 Y 结构配方图像 生物信息 主靶 GSK-3β 主靶IC50 18 nM for GSK-3&beta 纯度 ≥94% by HPLC 理化信息 细胞可渗透 Y 安全信息 R相 R: 36/38
Irritating to eyes and skin.S相 S: 26-36/37/39
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.储存和货运信息 货运代码 Dry Ice Only
毒性 Irritant
储存 -20°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze. Aliquots are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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