• merck millipore,默克密理博,191501,InSolution™ 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem
  • merck millipore,默克密理博,191501,InSolution™ 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem

    产品名称:InSolution™ 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem
    产品型号:191501
    A Kenpaullone analog that acts as a potent and ATP-competitive inhibitor of GSK-3&beta.

    merck millipore,默克密理博,191501,InSolution™ 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,191501,InSolution™ 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₅H₁₀BrN₃O676596-65-9
    描述
    概述 A Kenpaullone (Cat. No. 422000) analog that acts as a potent and ATP-competitive inhibitor of GSK-3β (IC50 = 18 nM). Displays over 100-fold greater selectivity over Cdk1/cyclin B and Cdk5/p25 (IC50 = 2.0 µM and 4.2 µM, respectively). The solid form of this compound (Cat. No. 191500) is also available.
    产品目录编号 191501
    品牌系列 Calbiochem®
    参考
    参考 Kunick, C., et al. 2004. Bioorg. Med. Chem. Lett. 14, 413.
    产品信息
    CAS号 676596-65-9
    形式 Liquid
    配方 A 10 mM (500 µg/152 µL) solution of 1-Azakenpaullone (Cat. No. 191500) in DMSO.
    Hill配方 C₁₅H₁₀BrN₃O
    化学配方 C₁₅H₁₀BrN₃O
    Molar Mass 328.2
    吸湿 Hygroscopic
    可逆 Y
    结构配方图像
    生物信息
    主靶 GSK-3β
    主靶IC50 18 nM for GSK-3&beta
    纯度 ≥94% by HPLC
    理化信息
    细胞可渗透 Y
    安全信息
    R相 R: 36/38

    Irritating to eyes and skin.
    S相 S: 26-36/37/39

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing, gloves and eye/face protection.
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Irritant
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze. Aliquots are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,191501,InSolution™ 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem

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