merck millipore,默克密理愽
  • merck millipore,默克密理博,189405,Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem

  • merck millipore,默克密理博,189405,Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem

    产品名称：Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem
    产品型号：189405
    The Aurora Kinase Inhibitor III, also referenced under CAS 879127-16-9, controls the biological activity of Aurora Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosp More>>

    merck millipore,默克密理博,189405,Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,189405,Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₁H₁₈F₃N₅O879127-16-9
    描述
    概述 A cell-permeable 2,4-dianilinopyrimidine compound that acts as an ATP-competitive, potent, but non-selective inhibitor of Aurora A (IC50 = 42 nM). At higher concentrations, also inhibits the activities of other kinases, such as Lck, Bmx, IGF-1R, and Syk (IC50 = 131, 386, 591, and 887 nM, respectively).
    产品目录编号 189405
    品牌系列 Calbiochem®
    同义词 Cyclopropanecarboxylic acid-(3-(4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino)-phenyl)-amide, Aurora Kinase Inhibitor III
    参考
    参考 Zhang, Q., et al. 2006. J. Am. Chem. Soc. 128, 2182.
    产品信息
    CAS号 879127-16-9
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₁H₁₈F₃N₅O
    化学配方 C₂₁H₁₈F₃N₅O
    Molar Mass 413.4
    可逆 Y
    结构配方图像
    生物信息
    主靶 Aurora Kinase A
    主靶IC50 42 nM against Aurora A; 131, 386, 591, and 887 nM, against Lck, Bmx, IGF-1R, and Syk , respectively
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,189405,Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,506106,p21-Activated Kinase Inhibitor III, IPA-3 - CAS 42521-82-4 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,AP132-K,Goat Anti-Rabbit IgG, Affinity Purified (1mg)


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