merck millipore,默克密理愽
  • merck millipore,默克密理博,176901,Anthrax Lethal Factor Protease Inhibitor, In-2-LF - Calbiochem

  • merck millipore,默克密理博,176901,Anthrax Lethal Factor Protease Inhibitor, In-2-LF - Calbiochem

    产品名称：Anthrax Lethal Factor Protease Inhibitor, In-2-LF - Calbiochem
    产品型号：176901
    The Anthrax Lethal Factor Protease Inhibitor, In-2-LF controls the biological activity of Anthrax Lethal Factor Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applic More>>

    merck millipore,默克密理博,176901,Anthrax Lethal Factor Protease Inhibitor, In-2-LF - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,176901,Anthrax Lethal Factor Protease Inhibitor, In-2-LF - Calbiochem

    重要规格表

    经验配方
    C₈₁H₁₅₀N₄₂O₁₇
    描述
    概述 A cell-permeable N-acetylated, C-hydroxamate derivative of a 14-mer peptide designed from the MEK-2 template that acts as a competitive inhibitor of Anthrax lethal factor (LF) metalloprotease (Ki = 1 nM). Also inhibits MEK-3 cleavage. Protects against Anthrax toxin induced cytotoxicity in RAW264.7 and J772.A1 cells.
    产品目录编号 176901
    品牌系列 Calbiochem®
    同义词 Anthrax LF Protease Inhibitor, Bacillus anthracis LF Protease Inhibitor, In-2-LF
    参考
    参考 Peinado, J.R., et al. 2004. Biochem. Biophys. Res. Commun. 321, 601.
    Tonello, F., et. al. 2002. Nature 418, 386.
    产品信息
    具有ATP竞争性 N
    形式 White lyophilized solid
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₈₁H₁₅₀N₄₂O₁₇
    化学配方 C₈₁H₁₅₀N₄₂O₁₇
    Molar Mass 1984.4
    吸湿 Hygroscopic
    肽序列 Ac-Gly-Tyr-βAla-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Val-Leu-Arg-NHOH
    可逆 N
    生物信息
    主靶 anthrax LF metalloprotease
    主靶Ki 1 nM against Anthrax lethal factor (LF) metalloprotease
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO, 5% Acetic acid, or H₂O
    肽序列 Ac-Gly-Tyr-βAla-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Val-Leu-Arg-NHOH
    储存和货运信息
    货运代码 Blue Ice Only
    毒性 Standard Handling
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,176901,Anthrax Lethal Factor Protease Inhibitor, In-2-LF - Calbiochem

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