• merck millipore,默克密理博,176871,Angiotensin Converting Enzyme, His•Tag, Human, Recombinant, NSO Cells
  • merck millipore,默克密理博,176871,Angiotensin Converting Enzyme, His•Tag, Human, Recombinant, NSO Cells

    产品名称:Angiotensin Converting Enzyme, His•Tag, Human, Recombinant, NSO Cells
    产品型号:176871


    merck millipore,默克密理博,176871,Angiotensin Converting Enzyme, His•Tag, Human, Recombinant, NSO Cells

  • 产品介绍
  • merck millipore,默克密理博,176871,Angiotensin Converting Enzyme, His•Tag, Human, Recombinant, NSO Cells

    重要规格表

    描述
    概述 Recombinant, human ACE ectodomain (amino acids 30-1261) fused at the C-terminus to a His•Tag® sequence and expressed in NSO cells. ACE is a zinc metallopeptidase that cleaves the C-terminal dipeptide from angiotensin I to produce the potent vasopressor octapeptide angiotensin II. Inactivates bradykinin by the sequential removal of two C-terminal dipeptides. ACE is a type I membrane protein that exists in two isoforms, somatic and germinal. By SDS-PAGE, the apparent molecular mass of the glycosylated protein appears larger than 120 kDa under either reducing or non-reducing condition.
    产品目录编号 176871
    品牌系列 Calbiochem®
    同义词 Peptidyl-Dipetidase A, ACE
    参考
    参考 Wakutani, Y., et al. 2002. Ann. N. Y. Acad. Sci. 977, 232.
    Hu, J., et al. 2001. J. Biol. Chem. 276, 47863.
    Kessler, S.P., et al. 2000. J. Biol. Chem. 275, 26259.
    Soubrier, F. et al. 1998. Proc. Natl. Acad. Sci. USA. 85, 9386.
    产品信息
    形式 Liquid
    配方 In 75 mM NaCl, 12.5 mM Tris, 500 nM ZnCl₂, 40% glycerol, pH 7.5.
    Molar Mass 120000
    生物信息
    纯度 ≥95% by SDS-PAGE
    特异活性 ≥1 unit/µg protein
    浓缩标签 Please refer to vial label for lot-specific concentration
    理化信息
    污染物 Endotoxins: ≤1.0 EU/µg ACE
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Standard Handling
    储存 ≤ -70°C
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C).

    merck millipore,默克密理博,176871,Angiotensin Converting Enzyme, His•Tag, Human, Recombinant, NSO Cells

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