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描述 产品目录编号 14-934 商名 - Upstate
描述 GCN2, active 概述 GCN2 (EIF2AK4) belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2S1) to downregulate protein synthesis in response to varied cellular stresses. 产品信息 演示 Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. 应用 主要应用 - Kinase Assay
生物信息 来源 N-terminal GST-tagged, recombinant, human GCN2 full length, expressed by baculovirus in Sf21 insect cells. The recombinant protein contains the amino acid substitution E556G with reference to GenPept NP_001013725. E556G is reported in GenPept CAH10626. 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NP_001013725
基因符号 - KIAA1338
- GCN2
- EIF2AK4
纯化方法 Purified using glutathione sepharose. 靶子系列 STE UniProt编号 - Q9P2K8
产品使用声明 质量保证 Routinely evaluated by phosphorylation of peptide RSRSRSRSRSRSRSR 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 10 µg 包装 Also available in 250μg size as catalog # 14-934M and in bulk as catalog # 14-934-K.
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