merck millipore,默克密理博,05-1587,Anti-FOXO3a/FKHRL1 Antibody, clone 15F7.2

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
R, H	IHC, WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	05-1587
Replaces	04-1007
描述	Anti-FOXO3a/FKHRL1 Antibody, clone 15F7.2
Alternate Names	Forkhead in rhabdomyosarcoma-like 1 Forkhead box protein O3 AF6q21 protein
背景信息	Forkhead box protein O3 (FOXO3a), or FKHRL1, is a ubiquitous transcription factor that triggers the expression of pro-apoptotic genes under conditions of oxidative stress. FOXO3a is regulated by the Akt kinase which phosphorylates FOXO3a on serine 253, 315, and on threonine 32 residues. Modified FOXO3a is recognized by the 14-3-3 proteins which export FOXO3a to the cytoplasm, and consequently terminates its transcriptional activity. FOXO3a may also be regulated by lysine methylation in neuronal cells.

产品信息
格式	Purified
控制	Rat liver tissue lysate.
演示	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Anti-FOXO3a/FKHRL1 Antibody, clone 15F7.2 is a Mouse Monoclonal Antibody for detection of FOXO3a/FKHRL1 also known as Forkhead box protein O3, AF6q21 protein, Forkhead in rhabdomyosarcoma-like 1 & has been validated in WB & IHC.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected FOXO3a/FKHRL1 in human thyroid gland tissue and human breast cancer tissue.

生物信息
免疫原品种	GST-tagged recombinant protein corresponding to human FOX03a.
克隆	15F7.2
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
同种型	IgG1κ
品种反应性	RatHuman
Species Reactivity Note	Demonstrated to react with Human and Rat.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_001446
基因符号	FOXO3A FOXO3 FKHRL1
纯化方法	Protein G purified
UniProt编号	O43524

产品使用声明
质量保证	Evaluated by Western Blot in rat liver tissue lysate. Western Blot Analysis: 0.2 µg/mL of this antibody detected FOXO3a/FKHRL1 in 10 mg of rat liver tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,05-1587,Anti-FOXO3a/FKHRL1 Antibody, clone 15F7.2

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