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描述 产品目录编号 14-926 商名 - Upstate
描述 IKKε Protein, active, 10 µg 概述 IKBKE is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage-induced cell death. 产品信息 演示 50mM Tris/HCl pH7.5, 150mM NaCl, 10mM β-glycerophosphate, 1mM sodium orthovanadate, 1mM NaF, 28% v/v glycerol, 0.03% Brij-35, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol 应用 应用 Active, N-terminal FLAG & GST-tagged, recombinant, human IKKε, full length. For use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 N-terminal FLAG and GST-tagged, recombinant, human IKK full length, expressed by baculovirus in Sf21 insect cells. 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_001193321.1
基因符号 - KIAA0151
- IKBKE
- IKKe
- IKKI
蛋白靶 IKKe 纯化方法 Purified by immunoaffinity chromatography. 靶子系列 Misc UniProt编号 - Q14164
产品使用声明 质量保证 Routinely evaluated by phosphorylation of casein. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 10 µg 包装 Also available in 250μg size as catalog # 14-926M and in bulk as catalog # 14-926-K.
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