- 当前位置:首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
描述 产品目录编号 14-844 品牌系列 Upstate
商名 - Upstate
描述 PIP5K1α Protein, active, 10 µg 概述 N-terminal 6His-tagged, recombinant human PIP5K1α, full length. 产品信息 演示 10µg of enzyme in 50mM Tris/HCl pH8.0, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 0.2mM PMSF, 1mM benzamidine, 0.1% 2-mercaptoethanol. Frozen solution. 应用 应用 Active, N-terminal 6His-tagged, recombinant human PIP5K1α, full length. For use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 Expressed by baculovirus in Sf21 insect cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - U78577
Entrez基因汇总 Participates in the biosynthesis of phosphatidylinositol-4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2 (By similarity) 基因符号 - PIP5K1A
蛋白靶 PIP5K1α 纯化方法 Immobilized metal affinity chromatography (IMAC) 靶子系列 PIPK UniProt编号 - Q99755
UniProt汇总 FUNCTION: Participates in the biosynthesis of phosphatidylinositol-4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2
CATALYTIC ACTIVITY: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
SUBUNIT STRUCTURE: Interacts with ARF1, RAC1, PLD1, PLD2 and JUB
SUBCELLULAR LOCATION: Cell membrane. Endomembrane system. Golgi apparatus › Golgi stack. Note: Associated with the plasma membrane and with internal membranes. Associated with Golgi stacks. Detected on RAC1-induced plasma membrane ruffles, and on membrane ruffles induced by platelet-derived growth factor.
TISSUE SPECIFICITY: Highly expressed in heart, placenta, skeletal muscle, kidney and pancreas. Detected at lower levels in brain, lung and liver.
SIMILARITY: Contains 1 PIPK domain.产品使用声明 质量保证 Routinely evaluated in the PIProfiler. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 10 µg 包装 Also available in 250μg size as catalog # 14-844M - Call for pricing and availability.
上一件merck millipore产品:merck millipore,默克密理博,6910-OP,OmniPur PIPES, Sodium Salt - CAS 100037-69-2 - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,210150,Cantharidic Acid - CAS 28874-45-5 - Calbiochem
merck millipore,默克密理博,06-1079,Anti-Interleukin 23 alpha (IL-23A) Antibody
merck millipore,默克密理博,MAB3582,Anti-Fascin Antibody, clone 55K2
merck millipore,默克密理博,17-409,EZ-Magna ChIP™ G - Chromatin Immunoprecipitation Kit
merck millipore,默克密理博,21-204,TOPglow (TCF reporter plasmid)
merck millipore,默克密理博,6910-OP,OmniPur PIPES, Sodium Salt - CAS 100037-69-2 - Calbiochem
merck millipore,默克密理博,210150,Cantharidic Acid - CAS 28874-45-5 - Calbiochem
merck millipore,默克密理博,SF-1972,CKS1B; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,373226,Hdm2 E3 Ligase Inhibitor II, HLI373 - CAS 502137-98-6 - Calbiochem
merck millipore,默克密理博,539684,PKA Inhibitor 6-22 Amide - CAS 121932-06-7 - Calbiochem




