merck millipore,默克密理愽
  • merck millipore,默克密理博,14-604M,PI3 Kinase (p110δ/p85α) Protein, active, 250 µg

  • merck millipore,默克密理博,14-604M,PI3 Kinase (p110δ/p85α) Protein, active, 250 µg

    产品名称：PI3 Kinase (p110δ/p85α) Protein, active, 250 µg
    产品型号：14-604M
    Active complex of N-terminal His6-tagged recombinant, full-length, human p110δ & untagged, recombinant, full length, human p85α. For use in Kinase Assays.

    merck millipore,默克密理博,14-604M,PI3 Kinase (p110δ/p85α) Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,14-604M,PI3 Kinase (p110δ/p85α) Protein, active, 250 µg

    描述
    产品目录编号 14-604M
    品牌系列 Upstate
    商名
    • Upstate
    描述 PI3 Kinase (p110δ/p85α) Protein, active, 250 µg
    概述 Complex of N-terminal His6-tagged recombinant, full-length, human p110δ and untagged, recombinant, full length, human p85α
    应用
    应用 Active complex of N-terminal His6-tagged recombinant, full-length, human p110δ & untagged, recombinant, full length, human p85α. For use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 Coexpressed by baculovirus in Sf21 insect cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_005026.2
    Entrez基因汇总 Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. See MIM 602838. The class I PI3Ks display a broad phosphoinositide lipid substrate specificity and include p110-alpha (MIM 171834), p110-beta (MIM 602925), and p110-gamma (MIM 601232). p110-alpha and p110-beta interact with SH2/SH3-domain-containing p85 adaptor proteins (see MIM 171833) and with GTP-bound Ras.[supplied by OMIM]
    基因符号
    • p110delta
    • PIK3CD
    • p110d
    • PI3K
    • p110D
    蛋白靶 PI3Kδ/p85α
    纯化方法 Ni2+/NTA-agarose
    靶子系列 PI3K/PI4K
    UniProt编号
    • O00329
    UniProt汇总 SIZE: 1044 amino acids; 119479 Da
    SUBUNIT: Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit. Interacts with ERAS (By similarity).
    TISSUE SPECIFICITY: Expressed predominantly in leukocytes.
    PTM: Autophosphorylation on Ser-1039 results in the almost complete inactivation of the lipid kinase activity.
    SIMILARITY: SwissProt: O00329 ## Belongs to the PI3/PI4-kinase family. & Contains 1 PI3K/PI4K domain.
    产品使用声明
    质量保证 routinely evaluated by the PIProfiler™
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 250 µg
    包装 Also available in 10 μg size (cat#14-604) and in bulk (cat# 14-604-K).

    merck millipore,默克密理博,14-604M,PI3 Kinase (p110δ/p85α) Protein, active, 250 µg

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