merck millipore,默克密理愽
  • merck millipore,默克密理博,14-602,PI3 Kinase (p110α/p85α) Protein, active, 20 µg

  • merck millipore,默克密理博,14-602,PI3 Kinase (p110α/p85α) Protein, active, 20 µg

    产品名称：PI3 Kinase (p110α/p85α) Protein, active, 20 µg
    产品型号：14-602
    Active complex of N-terminal His6-tagged recombinant full-length human p110α & untagged, recombinant, full length, human p85α. For use in Kinase Assays.

    merck millipore,默克密理博,14-602,PI3 Kinase (p110α/p85α) Protein, active, 20 µg

  • 产品介绍
  • merck millipore,默克密理博,14-602,PI3 Kinase (p110α/p85α) Protein, active, 20 µg

    描述
    产品目录编号 14-602
    品牌系列 Upstate
    商名
    • Upstate
    描述 PI3 Kinase (p110α/p85α) Protein, active, 20 µg
    概述 Complex of N-terminal His6-tagged recombinant full-length human p110α and untagged, recombinant, full length, human p85α
    应用
    应用 Active complex of N-terminal His6-tagged recombinant full-length human p110α & untagged, recombinant, full length, human p85α. For use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 Coexpressed by baculovirus in Sf21 insect cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_006218.2
    Entrez基因汇总 Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
    基因符号
    • MGC142163
    • PIK3CA
    • PI3K
    • MGC142161
    • p110-alpha
    蛋白靶 PI3Kα/p85α
    纯化方法 Ni2+/NTA-agarose
    靶子系列 PI3K/PI4K
    UniProt编号
    • P42336
    UniProt汇总 FUNCTION: SwissProt: P42336 # Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2.
    SIZE: 1068 amino acids; 124284 Da
    SUBUNIT: Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit. Binds to IRS1 in nuclear extracts. Interacts with RUFY3 (By similarity).
    DISEASE: SwissProt: P42336 # Defects in PIK3CA are associated with colorectal cancer (CRC) [MIM:114500]. & Defects in PIK3CA are associated with breast cancer [MIM:114480]. & Defects in PIK3CA are associated with epithelial ovarian cancer (EOC) [MIM:604370].
    SIMILARITY: SwissProt: P42336 ## Belongs to the PI3/PI4-kinase family. & Contains 1 C2 domain. & Contains 1 PI3K/PI4K domain.
    产品使用声明
    质量保证 routinely evaluated by PIProfiler
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 20 µg
    包装 Also available in 250μg size as catalog # 14-602M - Call for pricing and availability.

    merck millipore,默克密理博,14-602,PI3 Kinase (p110α/p85α) Protein, active, 20 µg

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