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描述 产品目录编号 14-521 品牌系列 Upstate
商名 - Upstate
描述 Arg Protein, active, human, 10 µg 概述 N-terminal His6-tagged recombinant human Arg, residues 38-end. 应用 应用 Active, human, N-terminal His6-tagged recombinant human Arg, residues 38-end. For use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 Human Arg expressed by baculovirus in Sf21 insect cells. 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_007314.1
- NM_005158.2
Entrez基因汇总 The gene product is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. This gene is expressed in both normal and tumor cells. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. 基因符号 - ARG
- ABL2
- Abelson-related
- ABLL
蛋白靶 Arg 纯化方法 Ni2+/NTA-agarose 靶子系列 TK UniProt编号 - P42684
UniProt汇总 FUNCTION: SwissProt: P42684 # Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics.
COFACTOR: Magnesium or manganese.
SIZE: 1182 amino acids; 128343 Da
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Widely expressed.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: P42684 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.产品使用声明 质量保证 Routinely evaluated by phosphorylation of Abltide. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 10 µg
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