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描述 概述 Native calpain-1 from porcine erythrocytes. Ca2+-dependent heterodimeric cysteine proteinase with low Ca2+ requirement (EC50= 2 µM). Participates in the ATP release reaction of platelets stimulated with thrombin. 产品目录编号 208712 品牌系列 Calbiochem®
同义词 μ-Calpain 参考 参考 Vanderklish, P.W., and Bahr, B.A. 2000. Int. J. Exp. Pathol. 81, 323.
Sorimachi, H., et al. 1997. Biochem. J. 328, 721.
Kampfl, A., et al. 1997. J. Neurotrauma 14, 121.
Johnson, G.V.W., and Gutmann, R.P. 1997. BioEssays 19, 1011.
Bartus, R.T., et al. 1995. Neurol. Res. 17, 249.
Wang, K.K.W., and Yuen, P.-W. 1994. Trends Pharmacol. Sci. 15, 412.
Saito, K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 2628.
Goll, D.E., et al. 1992. BioEssays 14, 549.
Ishii, H., et al. 1992. Biochim. Biophys. Acta 1175, 37.
Melloni, E., and Pontremoli, S. 1989. Trends Neurosci. 12, 438.
Ross, E., and Schatz, G. 1973. Anal. Biochem. 54, 304.产品信息 EC号 3.4.22.17 形式 Liquid 配方 In 20 mM imidazole-HCl, 5 mM β-mercaptoethanol, 1 mM EDTA, 1 mM EGTA, 30% glycerol, pH 6.8. Molar Mass 112000 PI 5.3 生物信息 特异活性 ≥1000 units/mg protein 浓缩标签 Please refer to vial label for lot-specific concentration
安全信息 R相 R: 36/37/38-42/43
Irritating to eyes, respiratory system and skin.
May cause sensitization by inhalation and skin contact.S相 S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.储存和货运信息 货运代码 Dry Ice Only
毒性 Harmful
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C). Short-term storage of aliquots at 4°C or on ice is not recommended.
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