merck millipore,默克密理愽
  • merck millipore,默克密理博,14-378,MKK4/SKK1 Protein, unactive, 50 µg

  • merck millipore,默克密理博,14-378,MKK4/SKK1 Protein, unactive, 50 µg

    产品名称：MKK4/SKK1 Protein, unactive, 50 µg
    产品型号：14-378
    Unactive, recombinant mouse MKK4, corresponding to amino acids 35-397, fused to an N-terminal GST-tag, for use in Kinase Assays.

    merck millipore,默克密理博,14-378,MKK4/SKK1 Protein, unactive, 50 µg

  • 产品介绍
  • merck millipore,默克密理博,14-378,MKK4/SKK1 Protein, unactive, 50 µg

    描述
    产品目录编号 14-378
    品牌系列 Upstate
    商名
    • Upstate
    描述 MKK4/SKK1 Protein, unactive, 50 µg
    概述 Recombinant mouse MKK4, corresponding to amino acids 35-397, fused to an Nterminal GST-tag
    应用
    应用 Unactive, recombinant mouse MKK4, corresponding to amino acids 35-397, fused to an N-terminal GST-tag, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 expressed in E. coli
    品种 Mouse
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_003010.2
    Entrez基因汇总 This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.
    基因符号
    • PRKMK4
    • MAP2K4
    • MKK4
    • JNKK
    • MEK4
    • MAPKK4
    • JNKK1
    • SEK1
    • SERK1
    蛋白靶 MKK4
    纯化方法 GSH-agarose chromatography
    靶子系列 STE
    UniProt编号
    • P45985
    UniProt汇总 FUNCTION: SwissProt: P45985 # Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).
    SIZE: 399 amino acids; 44288 Da
    SUBUNIT: Interacts with SPAG9 (By similarity).
    TISSUE SPECIFICITY: Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
    PTM: Activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases (By similarity).
    SIMILARITY: SwissProt: P45985 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of ATF2 substrate
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -20C
    包装信息
    数量 50 µg

    merck millipore,默克密理博,14-378,MKK4/SKK1 Protein, unactive, 50 µg

上一件merck millipore产品：merck millipore,默克密理博,ACS505002,Amicon Pro Purification System with 50kDa Amicon Ultra-0.5 Device
下一件merck millipore产品：merck millipore,默克密理博,AB1056,Anti-Adenovirus Antibody


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