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描述 产品目录编号 12-545 品牌系列 Upstate
商名 - Upstate
描述 ZIPtide 产品信息 演示 Lyophilized powder 应用 应用 ZIPtide primarily used in Kinase Assays. 主要应用 - Kinase Assay
生物信息 Entrez基因编号 - NM_001348.1
Entrez基因汇总 Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of apoptosis. 基因符号 - ZIP
- DAPK3
- FLJ36473
- ZIP-kinase
- Dlk
- ZIPK
蛋白靶 ZIPK 靶子系列 CAMK UniProt编号 - O43293
UniProt汇总 FUNCTION: SwissProt: O43293 # Serine/threonine kinase which acts as a positive regulator of apoptosis. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis.
COFACTOR: Magnesium.
SIZE: 454 amino acids; 52536 Da
SUBUNIT: Homodimer or forms heterodimers with ATF4. Both interactions require an intact leucine zipper domain and oligomerization is required for full enzymatic activity. Also binds to DAXX and PAWR, possibly in a ternary complex which plays a role in caspase activation. Interacts with AATF and CDC5L.
SUBCELLULAR LOCATION: Nucleus. Cytoplasm (By similarity). Note=Relocates to the cytoplasm on binding PAWR where the complex appears to interact with actin filaments (By similarity). Associates to centromeres from prophase to anaphase.
SIMILARITY: SwissProt: O43293 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. & Contains 1 protein kinase domain.产品使用声明 质量保证 Routinely evaluated as a substrate for ZIPK, active (14-608) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 1 mg
上一件merck millipore产品：merck millipore,默克密理博,07-030,Anti-dimethyl-Histone H3 (Lys4) Antibody
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