merck millipore,默克密理博,113000,Acridine Orange - CAS 65-61-2

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merck millipore,默克密理博,113000,Acridine Orange - CAS 65-61-2 - Calbiochem
产品名称：Acridine Orange - CAS 65-61-2 - Calbiochem
产品型号：113000

merck millipore,默克密理博,113000,Acridine Orange - CAS 65-61-2 - Calbiochem

产品介绍

merck millipore,默克密理博,113000,Acridine Orange - CAS 65-61-2 - Calbiochem

重要规格表

经验配方	CAS号
C₁₇H₂₀ClN₃	65-61-2

描述
概述	A cell-permeable, cationic fluorescent dye that interacts with DNA and RNA by intercalation or electrostatic attractions. When bound to DNA, it is spectrally very similar to fluorescein, with an excitation maximum at 502 nm and an emission maximum at 525 nm. Upon association with RNA, the excitation maximum shifts to 460 nm and the emission maximum shifts to 650 nm (red). Often used to measure single- and double-stranded DNA and RNA in the diagnosis, classification, and prognosis of many neoplasms. A very versatile fluorescent stain used in histochemistry and cytochemistry that can be used to provide information about the in situ content, molecular structure, and conformation of many nucleic acid-containing cell constituents.
产品目录编号	113000
品牌系列	Calbiochem®
同义词	AO, 3,6-bis(Dimethylamino)acridine, HCl

参考
参考	Gonzalez, K., et al. 1995. Curr. Eye Res. 14, 269. Muro-Cacho, C.A., et al. 1995. J. Immunol. 154, 5555. Olivier, R. 1995. Methods Enzymol. 251, 270. Busch, G.L., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 9165. Darzynkiewicz, Z. 1994. Methods Cell. Biol. 41, 401. Delic, J., et al. 1991. Exp. Cell Res. 194, 147. El-Naggar, A.K., et al. 1991. Cytometry 12, 330. Lopez, F., et al. 1991. Cytometry 12, 42. Gurrieri, S., et al. 1990. Biochemistry 29, 3396. Hermansen, D.K., et al. 1989. Cytometry 10, 739.

参考

Gonzalez, K., et al. 1995. Curr. Eye Res. 14, 269.
Muro-Cacho, C.A., et al. 1995. J. Immunol. 154, 5555.
Olivier, R. 1995. Methods Enzymol. 251, 270.
Busch, G.L., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 9165.
Darzynkiewicz, Z. 1994. Methods Cell. Biol. 41, 401.
Delic, J., et al. 1991. Exp. Cell Res. 194, 147.
El-Naggar, A.K., et al. 1991. Cytometry 12, 330.
Lopez, F., et al. 1991. Cytometry 12, 42.
Gurrieri, S., et al. 1990. Biochemistry 29, 3396.
Hermansen, D.K., et al. 1989. Cytometry 10, 739.

产品信息
CAS号	65-61-2
具有ATP竞争性	N
形式	Burnt-orange solid
Hill配方	C₁₇H₂₀ClN₃
化学配方	C₁₇H₂₀ClN₃
Molar Mass	301.8
吸湿	Hygroscopic
可逆	N
结构配方图像

生物信息
主靶	Interacts with DNA and RNA
纯度	≥98% by HPLC

理化信息
细胞可渗透	Y
溶解度	DMF, EtOH, or H₂O

GHS安全信息
RTECS	AR7601000

安全信息
R相	R: 20/21/22-40 Harmful by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect.
S相	S: 36 Wear suitable protective clothing.

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Harmful & Carcinogenic / Teratogenic
储存	+15°C to +30°C
避光	Protect from light
吸湿	Hygroscopic
无需冷冻	No
特殊指南	Following reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 1 month at 4°C.